Regulation of the human topoisomerase IIalpha gene promoter in confluence-arrested cells.
about
HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalphaICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cellsCasein kinase II catalyzes a mitotic phosphorylation on threonine 1342 of human DNA topoisomerase IIalpha, which is recognized by the 3F3/2 phosphoepitope antibody.Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase.The assembly of the CAAT-box binding complex at a photosynthesis gene promoter is regulated by light, cytokinin, and the stage of the plastids.Down-regulation of human topoisomerase IIalpha expression correlates with relative amounts of specificity factors Sp1 and Sp3 bound at proximal and distal promoter regionsInfluence of cell cycle and oncogene activity upon topoisomerase IIalpha expression and drug toxicity.A survey of 178 NF-Y binding CCAAT boxes.p53 regulates the minimal promoter of the human topoisomerase IIalpha gene.DNA topoisomerase II as a target for cancer chemotherapy.A 96-well DNase I footprinting screen for drug-DNA interactions.Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues.Inhibition of DNA topoisomerase II alpha gene expression by the p53 tumor suppressorConcurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells.Topoisomerase 2 alpha: a real predictor of anthracycline efficacy?Design of a hairpin polyamide, ZT65B, for targeting the inverted CCAAT box (ICB) site in the multidrug resistant (MDR1) gene.The role of an inverted CCAAT element in transcriptional activation of the human DNA topoisomerase IIalpha gene by heat shock.Transcriptional regulation of xyn2 in Hypocrea jecorina.C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.Topo II alpha reporter mice reveal proliferative regions in the epidermis and small intestine.The cyclin B2 promoter depends on NF-Y, a trimer whose CCAAT-binding activity is cell-cycle regulated.Sp1 mediates cell proliferation-dependent regulation of rat DNA topoisomerase IIalpha gene promoterCharacterization of the human topoisomerase IIbeta (TOP2B) promoter activity: essential roles of the nuclear factor-Y (NF-Y)- and specificity protein-1 (Sp1)-binding sites.TOP2A amplification and overexpression in hepatocellular carcinoma tissues.Modulation of DNA topoisomerase II alpha promoter activity by members of the Sp (specificity protein) and NF-Y (nuclear factor Y) families of transcription factors.c-Myb trans-activates the human DNA topoisomerase IIalpha gene promoter.Modulation of topoisomerase IIα expression and chemosensitivity through targeted inhibition of NF-Y:DNA binding by a diamino p-anisyl-benzimidazole (Hx) polyamide.Ras stimulates DNA topoisomerase II alpha through MEK: a link between oncogenic signaling and a therapeutic target.Evidence for repressional role of an inverted CCAAT box in cell cycle-dependent transcription of the human DNA topoisomerase IIalpha gene.NF-Y organizes the gamma-globin CCAAT boxes region.Dynamics of tobacco DNA topoisomerases II in cell cycle regulation: to manage topological constrains during replication, transcription and mitotic chromosome condensation and segregation.Topoisomerases as anticancer targets.
P2860
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P2860
Regulation of the human topoisomerase IIalpha gene promoter in confluence-arrested cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Regulation of the human topoisomerase IIalpha gene promoter in confluence-arrested cells.
@en
type
label
Regulation of the human topoisomerase IIalpha gene promoter in confluence-arrested cells.
@en
prefLabel
Regulation of the human topoisomerase IIalpha gene promoter in confluence-arrested cells.
@en
P2860
P356
P1476
Regulation of the human topoisomerase IIalpha gene promoter in confluence-arrested cells.
@en
P2093
P2860
P304
16741-16747
P356
10.1074/JBC.271.28.16741
P407
P577
1996-07-01T00:00:00Z