Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.
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Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthaseStructure-Based Design and Synthesis of N ω -Nitro- l -Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural WaterHeme-Coordinating Inhibitors of Neuronal Nitric Oxide Synthase. Iron−Thioether Coordination Is Stabilized by Hydrophobic Contacts without Increased Inhibitor PotencyAnchored plasticity opens doors for selective inhibitor design in nitric oxide synthasePotent, Highly Selective, and Orally Bioavailable Gem -Difluorinated Monocationic Inhibitors of Neuronal Nitric Oxide SynthaseExploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine DerivativesCyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthaseStructure-Guided Design of Selective Inhibitors of Neuronal Nitric Oxide SynthaseIntramolecular hydrogen bonding: A potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthaseIn search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structuresStructural and biological studies on bacterial nitric oxide synthase inhibitorsSelective Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Binding Mode Insights from Molecular Dynamics SimulationsPotent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of MelanomaNitric Oxide Synthase Inhibitors That Interact with Both Heme Propionate and Tetrahydrobiopterin Show High Isoform SelectivityRate, affinity and calcium dependence of nitric oxide synthase isoform binding to the primary physiological regulator calmodulinCharacterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerizationInteraction between caveolin-1 and the reductase domain of endothelial nitric-oxide synthase. Consequences for catalysisThe proline-rich domain of dynamin-2 is responsible for dynamin-dependent in vitro potentiation of endothelial nitric-oxide synthase activity via selective effects on reductase domain function.Characterization of a nitric oxide synthase from the plant kingdom: NO generation from the green alga Ostreococcus tauri is light irradiance and growth phase dependent.The expression of contextual fear conditioning involves activation of an NMDA receptor-nitric oxide pathway in the medial prefrontal cortex.Mutation of the five conserved histidines in the endothelial nitric-oxide synthase hemoprotein domain. No evidence for a non-heme metal requirement for catalysis.Glucose scavenging of nitric oxide.Dissecting the molecular control of endothelial NO synthase by caveolin-1 using cell-permeable peptidesSilent Partner in Blood Vessel Homeostasis? Pervasive Role of Nitric Oxide in Vascular Disease.Tetrahydrobiopterin, superoxide, and vascular dysfunction.The autoinhibitory control element and calmodulin conspire to provide physiological modulation of endothelial and neuronal nitric oxide synthase activity.Intraprotein electron transfer between the FMN and heme domains in endothelial nitric oxide synthase holoenzyme.Endothelial nitric oxide synthase is regulated by ERK phosphorylation at Ser602.Oxygen reduction by nitric-oxide synthases.Mechanism of Nitric Oxide Synthase Regulation: Electron Transfer and Interdomain Interactions.Holoenzyme structures of endothelial nitric oxide synthase - an allosteric role for calmodulin in pivoting the FMN domain for electron transferNitric oxide synthases activation and inhibition by metallacarborane-cluster-based isoform-specific affectors.Structure-based design of bacterial nitric oxide synthase inhibitors.Superoxide induces endothelial nitric-oxide synthase protein thiyl radical formation, a novel mechanism regulating eNOS function and coupling.Inhibitor-κB kinase attenuates Hsp90-dependent endothelial nitric oxide synthase function in vascular endothelial cells.Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors.Serine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation.Hydroxyethylene isosteres of selective neuronal nitric oxide synthase inhibitorsSuperoxide generation by endothelial nitric oxide synthase: the influence of cofactors.Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors
P2860
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P2860
Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.
@en
type
label
Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.
@en
prefLabel
Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.
@en
P2093
P356
P1476
Characterization of bovine endothelial nitric oxide synthase expressed in E. coli
@en
P2093
P304
P356
10.1006/BBRC.1996.0238
P407
P577
1996-02-01T00:00:00Z