Break dosage, cell cycle stage and DNA replication influence DNA double strand break response.
about
Nondisjunction of a single chromosome leads to breakage and activation of DNA damage checkpoint in G2Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeresAn overview of Cdk1-controlled targets and processesA fine-structure map of spontaneous mitotic crossovers in the yeast Saccharomyces cerevisiaeDNA resection in eukaryotes: deciding how to fix the breakDNA end resection: many nucleases make light workMechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeReplication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrityMultiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNASlx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA.Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.Recruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeastTel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand BreaksSUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damageA truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae.Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targetingSgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends.Effect of telomere proximity on telomere position effect, chromosome healing, and sensitivity to DNA double-strand breaks in a human tumor cell line.Microhomology-mediated end joining induces hypermutagenesis at breakpoint junctions.Extensive DNA end processing by exo1 and sgs1 inhibits break-induced replicationDNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.Timing is everything: cell cycle control of Rad52From the Cover: mitotic gene conversion events induced in G1-synchronized yeast cells by gamma rays are similar to spontaneous conversion events.Properties of Mitotic and Meiotic Recombination in the Tandemly-Repeated CUP1 Gene Cluster in the Yeast Saccharomyces cerevisiae.Initiation and completion of spontaneous mitotic recombination occur in different cell cycle phases.End resection at double-strand breaks: mechanism and regulation.Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human cancer cell lineSequence conversion by single strand oligonucleotide donors via non-homologous end joining in mammalian cellsRelease of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.Mechanisms and principles of homology search during recombination.ANG II promotes autophagy in podocytesKu prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2DNA resection at chromosome breaks promotes genome stability by constraining non-allelic homologous recombinationBRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle.The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1.Initiation of DNA damage responses through XPG-related nucleasesDNA end resection--unraveling the tail.RPA coordinates DNA end resection and prevents formation of DNA hairpins.New tools to study DNA double-strand break repair pathway choice.
P2860
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P2860
Break dosage, cell cycle stage and DNA replication influence DNA double strand break response.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Break dosage, cell cycle stage ...... double strand break response.
@en
type
label
Break dosage, cell cycle stage ...... double strand break response.
@en
prefLabel
Break dosage, cell cycle stage ...... double strand break response.
@en
P2860
P356
P1433
P1476
Break dosage, cell cycle stage ...... double strand break response.
@en
P2860
P304
P356
10.1038/EMBOJ.2008.111
P407
P577
2008-05-29T00:00:00Z