Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting
about
Telomere dysfunction and chromosome instabilityDNA repair by RNA: Templated, or not templated, that is the questionMechanisms underlying structural variant formation in genomic disordersSources of DNA double-strand breaks and models of recombinational DNA repairDNA dynamics during early double-strand break processing revealed by non-intrusive imaging of living cellsMigrating bubble during break-induced replication drives conservative DNA synthesis.The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends.Yeast Pif1 accelerates annealing of complementary DNA strands.Noncanonical views of homology-directed DNA repairAPOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA ReplicationTemporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctionsThe genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1.Sgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends.Microhomology-mediated end joining induces hypermutagenesis at breakpoint junctions.Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.The logic and mechanism of homologous recombination partner choiceCompetitive repair by naturally dispersed repetitive DNA during non-allelic homologous recombinationBreak-induced replication is highly inaccurateEnd resection at double-strand breaks: mechanism and regulation.Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitnessDNA resection at chromosome breaks promotes genome stability by constraining non-allelic homologous recombinationHigh-resolution mapping of two types of spontaneous mitotic gene conversion events in Saccharomyces cerevisiaeSgs1 and Exo1 suppress targeted chromosome duplication during ends-in and ends-out gene targeting.Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.Real-time analysis of double-strand DNA break repair by homologous recombinationDNA end resection--unraveling the tail.Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resectionBreak-induced replication is a source of mutation clusters underlying kataegisFragile site instability in Saccharomyces cerevisiae causes loss of heterozygosity by mitotic crossovers and break-induced replication.Cascades of genetic instability resulting from compromised break-induced replication.Hyper-Acetylation of Histone H3K56 Limits Break-Induced Replication by Inhibiting Extensive Repair Synthesis.RPA antagonizes microhomology-mediated repair of DNA double-strand breaks.PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells.Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair.DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous RecombinationMechanisms of telomere loss and their consequences for chromosome instability.Recombinational repair of radiation-induced double-strand breaks occurs in the absence of extensive resection.Yeast Helicase Pif1 Unwinds RNA:DNA Hybrids with Higher Processivity than DNA:DNA Duplexes.
P2860
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P2860
Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Defective resection at DNA dou ...... on and enhances gene targeting
@ast
Defective resection at DNA dou ...... on and enhances gene targeting
@en
Defective resection at DNA dou ...... n and enhances gene targeting.
@nl
type
label
Defective resection at DNA dou ...... on and enhances gene targeting
@ast
Defective resection at DNA dou ...... on and enhances gene targeting
@en
Defective resection at DNA dou ...... n and enhances gene targeting.
@nl
prefLabel
Defective resection at DNA dou ...... on and enhances gene targeting
@ast
Defective resection at DNA dou ...... on and enhances gene targeting
@en
Defective resection at DNA dou ...... n and enhances gene targeting.
@nl
P2093
P2860
P1433
P1476
Defective resection at DNA dou ...... on and enhances gene targeting
@en
P2093
Alma Papusha
Anna Malkova
Grzegorz Ira
Woo-Hyun Chung
P2860
P304
P356
10.1371/JOURNAL.PGEN.1000948
P577
2010-05-13T00:00:00Z