CDC42 inhibition suppresses progression of incipient intestinal tumors. - Wikidata - awgldk - TriplyDB

CDC42 inhibition suppresses progression of incipient intestinal tumors.

CDC42 inhibition suppresses progression of incipient intestinal tumors.

http://www.wikidata.org/entity/Q38966986

about

MicroRNAs in colorectal carcinoma--from pathogenesis to therapy Approaches of targeting Rho GTPases in cancer drug discovery Cancer Stem Cells and Radioresistance: Rho/ROCK Pathway Plea Attention Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer.Global ablation of the mouse Rab11a gene impairs early embryogenesis and matrix metalloproteinase secretion.miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells.Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche.RAB and RHO GTPases regulate intestinal crypt cell homeostasis and enterocyte function.A role for activated Cdc42 in glioblastoma multiforme invasion.A Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export.Rho GTPases: Anti- or pro-neoplastic targets?Molecular pathways driving disease-specific alterations of intestinal epithelial cells.Cytotoxic necrotizing factor 1 promotes prostate cancer progression through activating the Cdc42-PAK1 axis.Intestinal GPCRs Control Paneth Cell Maturation and Susceptibility to Experimental Colitis.Using 3D Organoid Cultures to Model Intestinal Physiology and Colorectal Cancer.Inhibition of the RhoGTPase Cdc42 by ML141 enhances hepatocyte differentiation from human adipose-derived mesenchymal stem cells via the Wnt5a/PI3K/miR-122 pathway: impact of the age of the donor.

P2860

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P2860

CDC42 inhibition suppresses progression of incipient intestinal tumors.

http://www.wikidata.org/entity/Q38966986

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

CDC42 inhibition suppresses progression of incipient intestinal tumors.

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type

label

CDC42 inhibition suppresses progression of incipient intestinal tumors.

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CDC42 inhibition suppresses progression of incipient intestinal tumors.

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0008-5472.CAN-14-0267

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Cancer Research

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CDC42 inhibition suppresses progression of incipient intestinal tumors.

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P2093

Alexis J Rodriguez

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Andrew Hoffman

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Chung S Yang

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Da-Hai Yu

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Edward M Bonder

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Francesca Walker

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Guangxun Li

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Jiang Fu

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Jiaxin Sun

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Lanlan Shen

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P2860

Asef, a link between the tumor suppressor APC and G-protein signaling

The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice

Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

Comprehensive molecular characterization of human colon and rectal cancer

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism

Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression

A genetic model for colorectal tumorigenesis

Identification of stem cells in small intestine and colon by marker gene Lgr5

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