UHRF1 is a sensor for DNA interstrand crosslinks and recruits FANCD2 to initiate the Fanconi anemia pathway.
about
Mechanisms of interstrand DNA crosslink repair and human disordersCellular response to DNA interstrand crosslinks: the Fanconi anemia pathwayExploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer TherapySignalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancerHemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1Epigenome Maintenance in Response to DNA DamageA cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choiceRepair Pathway Choices and Consequences at the Double-Strand BreakThe FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2.Proteomics insights into DNA damage response and translating this knowledge to clinical strategies.Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function.The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer.Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers.DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway.Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.UHRF1 is a sensor for DNA interstrand crosslinks.Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell.Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle.UHRF1 depletion sensitizes retinoblastoma cells to chemotherapeutic drugs via downregulation of XRCC4.An Intramolecular Interaction of UHRF1 Reveals Dual Control for Its Histone Association.Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection.Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a.Rare Genetic Diseases with Defects in DNA Repair: Opportunities and Challenges in Orphan Drug Development for Targeted Cancer Therapy
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P2860
UHRF1 is a sensor for DNA interstrand crosslinks and recruits FANCD2 to initiate the Fanconi anemia pathway.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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name
UHRF1 is a sensor for DNA inte ...... te the Fanconi anemia pathway.
@en
UHRF1 is a sensor for DNA inte ...... te the Fanconi anemia pathway.
@nl
type
label
UHRF1 is a sensor for DNA inte ...... te the Fanconi anemia pathway.
@en
UHRF1 is a sensor for DNA inte ...... te the Fanconi anemia pathway.
@nl
prefLabel
UHRF1 is a sensor for DNA inte ...... te the Fanconi anemia pathway.
@en
UHRF1 is a sensor for DNA inte ...... te the Fanconi anemia pathway.
@nl
P2093
P2860
P50
P1433
P1476
UHRF1 is a sensor for DNA inte ...... ate the Fanconi anemia pathway
@en
P2093
Wilhelm Haas
Yasunaga Yoshikawa
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P304
P356
10.1016/J.CELREP.2015.02.053
P577
2015-03-19T00:00:00Z