Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition.
about
Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cellsA quarter century of granzymesThe major human and mouse granzymes are structurally and functionally divergentApoptosis: a review of programmed cell deathMcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cellsCharacterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compoundGranzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis.Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis.Human ovarian tumor cells escape γδ T cell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules.Natural killer cells eradicate galectin-1-deficient glioma in the absence of adaptive immunity.Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis.Granzymes and perforin in solid organ transplant rejection.Toxoplasma gondii inhibits granzyme B-mediated apoptosis by the inhibition of granzyme B function in host cellsImportance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B.Granzyme B-induced mitochondrial ROS are required for apoptosisAltered autoantigen structure in Sjögren's syndrome: implications for the pathogenesis of autoimmune tissue damage.Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110Apoptosis in normal and diseased oral tissues.Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis.A molecular view of cytotoxic T lymphocyte induced killing.X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity.miR-143 or miR-145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells.Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8(+) T cells and dendritic cells.Mechanisms of granule-dependent killing.Cell-centric view of apoptosis and apoptotic cell death-inducing antitumoral strategiesA proteomic approach for the discovery of protease substrates.Perforin and Fas act together in the induction of apoptosis, and both are critical in the clearance of lymphocytic choriomeningitis virus infection.Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma.Metallomics insights into the programmed cell death induced by metal-based anticancer compounds.Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.Second mitochondria-derived activator of caspase (SMAC) mimetic potentiates tumor susceptibility toward natural killer cell-mediated killing.Hop cleavage and function in granzyme B-induced apoptosis.Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules.Exocytosis and Fas mediated cytolytic mechanisms exert protection from West Nile virus induced encephalitis in mice.Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells.Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element.Targeting and amplification of immune killing of tumor cells by pro-Smac.Overexpression of Interleukin-15 increases susceptibility to lipopolysaccharide-induced liver injury in mice primed with Mycobacterium bovis bacillus Calmette-Guerin.The impact of ageing on natural killer cell function and potential consequences for health in older adults
P2860
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P2860
Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Granzyme B-induced apoptosis r ...... relief of caspase inhibition.
@en
Granzyme B-induced apoptosis r ...... relief of caspase inhibition.
@nl
type
label
Granzyme B-induced apoptosis r ...... relief of caspase inhibition.
@en
Granzyme B-induced apoptosis r ...... relief of caspase inhibition.
@nl
prefLabel
Granzyme B-induced apoptosis r ...... relief of caspase inhibition.
@en
Granzyme B-induced apoptosis r ...... relief of caspase inhibition.
@nl
P2093
P1433
P1476
Granzyme B-induced apoptosis r ...... relief of caspase inhibition.
@en
P2093
Allison M Hunter
Ing Swie Goping
Irene Shostak
Karolina M Michalak
Michele Barry
Peter Liston
R Chris Bleackley
Robert Korneluk
Tracy Sawchuk
P304
P356
10.1016/S1074-7613(03)00032-3
P407
P577
2003-03-01T00:00:00Z