High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives.
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New vitamin D analogs as potential therapeutics in melanomaDecreased VDR expression in cutaneous melanomas as marker of tumor progression: new data and analysesMelatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathwaysImmunohistochemical evaluation of vitamin D receptor (VDR) expression in cutaneous melanoma tissues and four VDR gene polymorphisms.Metabolism of 20-hydroxyvitamin D3 by mouse liver microsomesKey role of CRF in the skin stress response system.High GPX1 expression promotes esophageal squamous cell carcinoma invasion, migration, proliferation and cisplatin-resistance but can be reduced by vitamin DThe role of melanogenesis in regulation of melanoma behavior: melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways.CYP24A1 expression inversely correlates with melanoma progression: clinic-pathological studies.Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas.Metabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1Antitumor effects of vitamin D analogs on hamster and mouse melanoma cell lines in relation to melanin pigmentation.Melanoma Expressed-CD70 Is Regulated by RhoA and MAPK Pathways without Affecting Vemurafenib Treatment Activity.Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture.Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland.In vivo evidence for a novel pathway of vitamin D₃ metabolism initiated by P450scc and modified by CYP27B1.On the role of skin in the regulation of local and systemic steroidogenic activities.Total synthesis of biologically active 20S-hydroxyvitamin D3.Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytesExpression of the vitamin D-activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progressionNovel activities of CYP11A1 and their potential physiological significance.Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.Cytochromes p450 and skin cancer: role of local endocrine pathways.Melanin content in melanoma metastases affects the outcome of radiotherapy.Novel vitamin D photoproducts and their precursors in the skin.RORα and RORγ expression inversely correlates with human melanoma progression.Noncalcemic 20-hydroxyvitamin D3 inhibits human melanoma growth in in vitro and in vivo modelsIn vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions.Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation.Vitamin D in cancer chemoprevention.On the role of classical and novel forms of vitamin D in melanoma progression and management.Antiproliferative Activity of Double Point Modified Analogs of 1,25-Dihydroxyvitamin D₂ Against Human Malignant Melanoma Cell Lines.Effects of sidechain length and composition on the kinetic conversion and product distribution of vitamin D analogs determined by real-time NMR.Novel vitamin D hydroxyderivatives inhibit melanoma growth and show differential effects on normal melanocytes.20-hydroxyvitamin D₃ inhibits proliferation of cancer cells with high efficacy while being non-toxic.Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols.Rat CYP24A1 acts on 20-hydroxyvitamin D(3) producing hydroxylated products with increased biological activity.Synthesis and Biological Evaluation of Vitamin D3 Metabolite 20S,23S-Dihydroxyvitamin D3 and Its 23R Epimer.Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength.
P2860
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P2860
High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
High basal NF-κB activity in n ...... ity to vitamin D3 derivatives.
@en
High basal NF-κB activity in n ...... ity to vitamin D3 derivatives.
@nl
type
label
High basal NF-κB activity in n ...... ity to vitamin D3 derivatives.
@en
High basal NF-κB activity in n ...... ity to vitamin D3 derivatives.
@nl
prefLabel
High basal NF-κB activity in n ...... ity to vitamin D3 derivatives.
@en
High basal NF-κB activity in n ...... ity to vitamin D3 derivatives.
@nl
P2093
P2860
P50
P921
P356
P1476
High basal NF-κB activity in n ...... vity to vitamin D3 derivatives
@en
P2093
A A Brozyna
L M Pfeffer
M N Nguyen
S R Pfeffer
Z Janjetovic
P2860
P2888
P304
P356
10.1038/BJC.2011.458
P407
P577
2011-11-17T00:00:00Z