Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia
about
Regulation of mTORC1 by PI3K signalingTherapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shiftSuppression of replicative senescence by rapamycin in rodent embryonic cellsHypoxia induces permeability and giant cell responses of Andes virus-infected pulmonary endothelial cells by activating the mTOR-S6K signaling pathway.Molecular genetics of clear-cell renal cell carcinomaHantavirus interferon regulation and virulence determinantsHypoxia suppresses conversion from proliferative arrest to cellular senescence.Evolving Lessons on the Complex Role of AMPK in Normal Physiology and Cancer.Stratification of clear cell renal cell carcinoma by signaling pathway analysis.RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature.Hypoxia and gerosuppression: the mTOR saga continuesThe biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness.Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β-cell mass: implications in the development of type-2 diabetes.Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies.Furthering the design and the discovery of small molecule ATP-competitive mTOR inhibitors as an effective cancer treatment.Signal integration by mTORC1 coordinates nutrient input with biosynthetic output.Transcriptional regulation of the stress response by mTOR.Regulation of TFEB and V-ATPases by mTORC1.Signaling pathways and mechanisms of hypoxia-induced autophagy in the animal cells.Suppression of the proliferation of hypoxia-Induced retinal pigment epithelial cell by rapamycin through the /mTOR/HIF-1α/VEGF/ signaling.Interplay between pVHL and mTORC1 pathways in clear-cell renal cell carcinoma.Suppression of REDD1 in osteoarthritis cartilage, a novel mechanism for dysregulated mTOR signaling and defective autophagyREDD1/DDIT4-independent mTORC1 inhibition and apoptosis by glucocorticoids in thymocytesLKB1 obliterates Snail stability and inhibits pancreatic cancer metastasis in response to metformin treatment.Hypoxic Signalling in Tumour Stroma.Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1α signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivoHypoxia and Selective Autophagy in Cancer Development and Therapy
P2860
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P2860
Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Cell-type-dependent regulation ...... nd LKB1 in response to hypoxia
@en
Cell-type-dependent regulation ...... d LKB1 in response to hypoxia.
@nl
type
label
Cell-type-dependent regulation ...... nd LKB1 in response to hypoxia
@en
Cell-type-dependent regulation ...... d LKB1 in response to hypoxia.
@nl
prefLabel
Cell-type-dependent regulation ...... nd LKB1 in response to hypoxia
@en
Cell-type-dependent regulation ...... d LKB1 in response to hypoxia.
@nl
P2093
P2860
P356
P1476
Cell-type-dependent regulation ...... nd LKB1 in response to hypoxia
@en
P2093
Diego H Castrillon
James Brugarolas
Nicholas C Wolff
Silvia Vega-Rubin-de-Celis
Wareef Kabbani
Xian-Jin Xie
P2860
P304
P356
10.1128/MCB.01393-10
P407
P577
2011-03-07T00:00:00Z