CKIα ablation highlights a critical role for p53 in invasiveness control.
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The CK1 Family: Contribution to Cellular Stress Response and Its Role in CarcinogenesisNeuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosisThe β-catenin destruction complexExploiting the MDM2-CK1α protein-protein interface to develop novel biologics that induce UBL-kinase-modification and inhibit cell growthRepurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposisIdentification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical ProteomicsThe Genetic Architecture of Murine Glutathione TransferasesInflammation meets cancer, with NF-κB as the matchmakerObligate progression precedes lung adenocarcinoma dissemination.Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.Cryptopleurine analogs with modification of e ring exhibit different mechanism to rac-cryptopleurine and tylophorineVav1 fine tunes p53 control of apoptosis versus proliferation in breast cancerTelomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity.Integral analysis of p53 and its value as prognostic factor in sporadic colon cancerCSNK1α1 mediates malignant plasma cell survival.Activating CAR and β-catenin induces uncontrolled liver growth and tumorigenesis.Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formationPhosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer.A screen for X-linked mutations affecting Drosophila photoreceptor differentiation identifies Casein kinase 1α as an essential negative regulator of wingless signaling.Towards an understanding of the role of p53 in adrenocortical carcinogenesis.Casein kinase 1α has a non-redundant and dominant role within the CK1 family in melanoma progressionTransformation of the intestinal epithelium by the MSI2 RNA-binding protein.The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.Recent discoveries in the cycling, growing and aging of the p53 fieldThe nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferationAssessing cell and organ senescence biomarkersRadiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses.Widespread parainflammation in human cancer.Positive regulation of β-catenin-PROX1 signaling axis by DBC1 in colon cancer progression.The interplay between HPIP and casein kinase 1α promotes renal cell carcinoma growth and metastasis via activation of mTOR pathway.Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways.Deconstructing p53 transcriptional networks in tumor suppression.Regulation of NF-κB by ubiquitination and degradation of the IκBs.Transcription factor PROX1: its role in development and cancer.Maintenance of genomic integrity after DNA double strand breaks in the human prostate and seminal vesicle epithelium: the best and the worst.Genomic insights into WNT/β-catenin signaling.Unravelling mechanisms of p53-mediated tumour suppression.
P2860
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P2860
CKIα ablation highlights a critical role for p53 in invasiveness control.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
CKIα ablation highlights a critical role for p53 in invasiveness control.
@en
CKIα ablation highlights a critical role for p53 in invasiveness control.
@nl
type
label
CKIα ablation highlights a critical role for p53 in invasiveness control.
@en
CKIα ablation highlights a critical role for p53 in invasiveness control.
@nl
prefLabel
CKIα ablation highlights a critical role for p53 in invasiveness control.
@en
CKIα ablation highlights a critical role for p53 in invasiveness control.
@nl
P2093
P2860
P356
P1433
P1476
CKIα ablation highlights a critical role for p53 in invasiveness control.
@en
P2093
Ariel Pribluda
Ela Elyada
Eli Pikarsky
Gady Cojocaru
Guy Brachya
Ido Burstain
Irit Snir-Alkalay
Moshe Oren
Rebecca Haffner-Krausz
Robert E Goldstein
P2860
P2888
P304
P356
10.1038/NATURE09673
P407
P577
2011-02-01T00:00:00Z