Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie.
about
Biochemical properties of highly neuroinvasive prion strainsIncreased interleukin-17 in the cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease: a case-control study of rapidly progressive dementiaRepetitive immunization enhances the susceptibility of mice to peripherally administered prions.Genes contributing to prion pathogenesisPrion replication in the hematopoietic compartment is not required for neuroinvasion in scrapie mouse model.Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells.Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cellsExtraneural prion neuroinvasion without lymphoreticular system infection.Biological network inferences for a protection mechanism against familial Creutzfeldt-Jakob disease with E200K pathogenic mutation.Resistance of neonatal mice to scrapie is associated with inefficient infection of the immature spleen.Neuroinflammation in Alzheimer's disease and prion disease.The transmissible spongiform encephalopathies: pathogenic mechanisms and strategies for therapeutic intervention.The pathophysiology of variant Creutzfeldt-Jacob disease: the hypotheses behind concerns for blood components and products.The effects of host age on the transport of complement-bound complexes to the spleen and the pathogenesis of intravenous scrapie infection.Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes.Rational targeting for prion therapeutics.Progress in prion vaccines and immunotherapies.Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie.Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease SusceptibilityEarly cytokine elevation, PrPres deposition, and gliosis in mouse scrapie: no effect on disease by deletion of cytokine genes IL-12p40 and IL-12p35.Prion diseases and the gastrointestinal tract.Prions and their lethal journey to the brain.Prions and lymphoid organs: solved and remaining mysteries.The spread of prions through the body in naturally acquired transmissible spongiform encephalopathies.Role of the lymphoreticular system in prion neuroinvasion from the oral and nasal mucosaAnalysis of protein levels of 24 cytokines in scrapie agent-infected brain and glial cell cultures from mice differing in prion protein expression levelsAccelerated prion disease in the absence of interleukin-10.Neuroinvasion in prion diseases: the roles of ascending neural infection and blood dissemination.Prion disease and the innate immune system.Role of interleukin-1 in prion disease-associated astrocyte activation.Prion pathogenesis and secondary lymphoid organs (SLO): tracking the SLO spread of prions to the brainc-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium.The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity.Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen.Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brainProcessing and degradation of exogenous prion protein by CD11c(+) myeloid dendritic cells in vitroFollicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibilityNeuroinvasion by scrapie following inoculation via the skin is independent of migratory Langerhans cells.Comparison of inflammatory and acute-phase responses in the brain and peripheral organs of the ME7 model of prion diseaseFollicular dendritic cell dedifferentiation reduces scrapie susceptibility following inoculation via the skin.
P2860
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P2860
Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Tumor necrosis factor alpha-de ...... pheral infection with scrapie.
@en
Tumor necrosis factor alpha-de ...... pheral infection with scrapie.
@nl
type
label
Tumor necrosis factor alpha-de ...... pheral infection with scrapie.
@en
Tumor necrosis factor alpha-de ...... pheral infection with scrapie.
@nl
prefLabel
Tumor necrosis factor alpha-de ...... pheral infection with scrapie.
@en
Tumor necrosis factor alpha-de ...... pheral infection with scrapie.
@nl
P2093
P2860
P1433
P1476
Tumor necrosis factor alpha-de ...... pheral infection with scrapie.
@en
P2093
Farquhar CF
Mabbott NA
Pasparakis M
Williams A
P2860
P304
P356
10.1128/JVI.74.7.3338-3344.2000
P407
P577
2000-04-01T00:00:00Z