Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids.
about
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signalingFunctional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteasesThe rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfersExpression of a novel gene, gluP, is essential for normal Bacillus subtilis cell division and contributes to glucose exportThe roles of intramembrane proteases in protozoan parasitesRhomboid 4 (ROM4) affects the processing of surface adhesins and facilitates host cell invasion by Toxoplasma gondiiMaking the cut: central roles of intramembrane proteolysis in pathogenic microorganismsStructural basis for intramembrane proteolysis by rhomboid serine proteasesThe crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis.Open-cap conformation of intramembrane protease GlpGThe structural basis for catalysis and substrate specificity of a rhomboid proteaseProcessing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.Mitochondrial membrane remodelling regulated by a conserved rhomboid protease.Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malariaAllosteric regulation of rhomboid intramembrane proteolysisA Trichomonas vaginalis Rhomboid Protease and Its Substrate Modulate Parasite Attachment and Cytolysis of Host CellsStructures of membrane proteins.Structure and mechanism of rhomboid proteaseRHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer.BofA protein inhibits intramembrane proteolysis of pro-sigmaK in an intercompartmental signaling pathway during Bacillus subtilis sporulation.Monocyclic β-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteasesReconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity.Mutagenesis mapping of the presenilin 1 calcium leak conductance pore.A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma.Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole.A fly's eye view of EGF receptor signallingSharpening rhomboid specificity by dimerisation and allostery.Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family.Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.Functional analysis of rhomboid proteases during Toxoplasma invasion.Functional characterization of Escherichia coli GlpG and additional rhomboid proteins using an aarA mutant of Providencia stuartii.Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate.An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion.Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysisDerlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum.Membrane proteases in the bacterial protein secretion and quality control pathway.The membrane anchor of the transcriptional activator SREBP is characterized by intrinsic conformational flexibility.iRhoms; Its Functions and Essential Roles.Signal integration during development: mechanisms of EGFR and Notch pathway function and cross-talk.Soluble oligomers of the intramembrane serine protease YqgP are catalytically active in the absence of detergents.
P2860
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P2860
Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Conservation of intramembrane ...... otic and eukaryotic rhomboids.
@en
Conservation of intramembrane ...... otic and eukaryotic rhomboids.
@nl
type
label
Conservation of intramembrane ...... otic and eukaryotic rhomboids.
@en
Conservation of intramembrane ...... otic and eukaryotic rhomboids.
@nl
prefLabel
Conservation of intramembrane ...... otic and eukaryotic rhomboids.
@en
Conservation of intramembrane ...... otic and eukaryotic rhomboids.
@nl
P2093
P1433
P1476
Conservation of intramembrane ...... otic and eukaryotic rhomboids.
@en
P2093
Daniel Schlieper
Matthew Freeman
Sinisa Urban
P304
P356
10.1016/S0960-9822(02)01092-8
P407
P577
2002-09-01T00:00:00Z