Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway.
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The Nrf2/HO-1 Axis in Cancer Cell Growth and ChemoresistanceMultiple roles of Nrf2-Keap1 signaling: regulation of development and xenobiotic response using distinct mechanismsCytoprotection "gone astray": Nrf2 and its role in cancerWhole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiencyGrowth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python.HO-1/EBP interaction alleviates cholesterol-induced hypoxia through the activation of the AKT and Nrf2/mTOR pathways and inhibition of carbohydrate metabolism in cardiomyocytesTongue carcinoma infrequently harbor common actionable genetic alterationsNRF2 and cancer: the good, the bad and the importance of context.Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells.KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancerClinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancerDual roles of NRF2 in tumor prevention and progression: possible implications in cancer treatmentRapamycin increases oxidative stress response gene expression in adult stem cells.Correlation Between Nuclear Factor E2-Related Factor 2 Expression and Gastric Cancer Progression.Correlation between expression of NF-E2-related factor 2 and progression of gastric cancer.Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease.NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies.The involvement of NRF2 in lung cancerSQSTM1 is a pathogenic target of 5q copy number gains in kidney cancer.Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway.A novel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2 function in ovarian cancer cells.The cytoprotective role of the Keap1-Nrf2 pathway.Fumarate hydratase inactivation in renal tumors: HIF1α, NRF2, and "cryptic targets" of transcription factorsTranscriptional regulation of the stress response by mTOR.Computational probing protein-protein interactions targeting small molecules.The NRF2 knockout rat: a new animal model to study endothelial dysfunction, oxidant stress, and microvascular rarefaction.Nrf2 Transcription Factor Can Directly Regulate mTOR: LINKING CYTOPROTECTIVE GENE EXPRESSION TO A MAJOR METABOLIC REGULATOR THAT GENERATES REDOX ACTIVITY.HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation.Prevention of tumor growth by needle-free jet injection of anti-C7orf24 siRNA.Nrf2 knockdown by shRNA inhibits tumor growth and increases efficacy of chemotherapy in cervical cancer.Role of nuclear factor (erythroid-derived 2)-like 2 in metabolic homeostasis and insulin action: A novel opportunity for diabetes treatment?Perspectives of the Nrf-2 signaling pathway in cancer progression and therapy.Milk's Role as an Epigenetic Regulator in Health and DiseaseRagD gene expression and NRF2 mutations in lung squamous cell carcinomas.NRF2-regulated metabolic gene signature as a prognostic biomarker in non-small cell lung cancer.Analysis of apoptosis methods recently used in Cancer Research and Cell Death & Disease publications.Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer.Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer.Nrf2 promotes progression of non-small cell lung cancer through activating autophagy.NRF2 Addiction in Cancer Cells.
P2860
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P2860
Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Global downstream pathway anal ...... mTOR growth signaling pathway.
@en
Global downstream pathway anal ...... mTOR growth signaling pathway.
@nl
type
label
Global downstream pathway anal ...... mTOR growth signaling pathway.
@en
Global downstream pathway anal ...... mTOR growth signaling pathway.
@nl
prefLabel
Global downstream pathway anal ...... mTOR growth signaling pathway.
@en
Global downstream pathway anal ...... mTOR growth signaling pathway.
@nl
P2093
P1433
P1476
Global downstream pathway anal ...... mTOR growth signaling pathway
@en
P2093
Akiko Kokubu
Masayuki Yamamoto
Setsuo Hirohashi
Tatsuhiro Shibata
P304
P356
10.1158/0008-5472.CAN-10-0384
P407
P577
2010-11-09T00:00:00Z