Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression.
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Human AP endonuclease 1: a potential marker for the prediction of environmental carcinogenesis riskAPE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survivalInduction of apurinic endonuclease 1 overexpression by endoplasmic reticulum stress in hepatoma cells.Role of the DNA base excision repair protein, APE1 in cisplatin, oxaliplatin, or carboplatin induced sensory neuropathyRedox regulation of apurinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitisDual regulatory roles of human AP-endonuclease (APE1/Ref-1) in CDKN1A/p21 expressionApurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2.Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization.Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growthExploiting base excision repair to improve therapeutic approaches for pancreatic cancerApurinic/Apyrimidinic endonuclease 1 regulates inflammatory response in macrophages.Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease.Balancing repair and tolerance of DNA damage caused by alkylating agentsApurinic/apyrimidinic endonuclease-1 (APE-1) is overexpressed via the activation of NF-κB-p65 in MCP-1-positive esophageal squamous cell carcinoma tissue.Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.Apurinic/apyrimidinic endonuclease-1 is associated with angiogenesis and VEGF production via upregulation of COX-2 expression in esophageal cancer tissuesRegulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.APE1 overexpression promotes the progression of ovarian cancer and serves as a potential therapeutic target.Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral NeuropathyDesign and synthesis of 3-carbamoylbenzoic acid derivatives as inhibitors of human apurinic/apyrimidinic endonuclease 1 (APE1).Deregulation of base excision repair gene expression and enhanced proliferation in head and neck squamous cell carcinoma.DNA damage mediates changes in neuronal sensitivity induced by the inflammatory mediators, MCP-1 and LPS, and can be reversed by enhancing the DNA repair function of APE1.APE1/Ref-1 knockdown in pancreatic ductal adenocarcinoma - characterizing gene expression changes and identifying novel pathways using single-cell RNA sequencing.Bu-Fei decoction and modified Bu-Fei decoction inhibit the growth of non-small cell lung cancer, possibly via inhibition of apurinic/apyrimidinic endonuclease 1.APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells.Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.
P2860
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P2860
Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Reduced expression of DNA repa ...... n, and cell cycle progression.
@en
Reduced expression of DNA repa ...... n, and cell cycle progression.
@nl
type
label
Reduced expression of DNA repa ...... n, and cell cycle progression.
@en
Reduced expression of DNA repa ...... n, and cell cycle progression.
@nl
prefLabel
Reduced expression of DNA repa ...... n, and cell cycle progression.
@en
Reduced expression of DNA repa ...... n, and cell cycle progression.
@nl
P2093
P2860
P1433
P1476
Reduced expression of DNA repa ...... on, and cell cycle progression
@en
P2093
George E Sandusky
Mark R Kelley
Shaoyu Zhou
Yanlin Jiang
P2860
P304
P356
10.3109/07357907.2010.512816
P577
2010-11-01T00:00:00Z