Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group.

Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group.

Item
http://www.wikidata.org/entity/Q39736063
Investigating the Selectivity of Metalloenzyme Inhibitors in the Presence of Competing Metalloproteins.Novel histone deacetylase 8 ligands without a zinc chelating group: exploring an 'upside-down' binding pose.Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers.Investigating the selectivity of metalloenzyme inhibitors.Microbial natural products: molecular blueprints for antitumor drugs.Targeting the histone orthography of cancer: drugs for writers, erasers and readers.Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia.The effect of metalloprotein inhibitors on cellular metal ion content and distribution.Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes.The effect of various zinc binding groups on inhibition of histone deacetylases 1-11.Macrocyclic peptoid-Peptide hybrids as inhibitors of class I histone deacetylases.Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth.Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A.Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity.
P2860

Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group.

Item
http://www.wikidata.org/entity/Q39736063
description
2012 nî lūn-bûn
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2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Discovery of HDAC Inhibitors That Lack an Active Site Zn
@nl
Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group.
@en
type
label
Discovery of HDAC Inhibitors That Lack an Active Site Zn
@nl
Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group.
@en
prefLabel
Discovery of HDAC Inhibitors That Lack an Active Site Zn
@nl
Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932