Characterization of mutant myosins of Dictyostelium discoideum equivalent to human familial hypertrophic cardiomyopathy mutants. Molecular force level of mutant myosins may have a prognostic implication
about
The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosinMyosin dynamics on the millisecond time scale.Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay.The R403Q myosin mutation implicated in familial hypertrophic cardiomyopathy causes disorder at the actomyosin interfaceMyosin individualized: single nucleotide polymorphisms in energy transduction.The molecular genetic basis for hypertrophic cardiomyopathy.Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400Hypertrophic cardiomyopathy: from genetics to treatmentExperimental therapies in hypertrophic cardiomyopathyMutation of the myosin converter domain alters cross-bridge elasticity.Molecular genetics and pathogenesis of hypertrophic cardiomyopathy.Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy.Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy.Cell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy.Functional analyses of troponin T mutations that cause hypertrophic cardiomyopathy: insights into disease pathogenesis and troponin function.Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backboneMuscle dysfunction in hypertrophic cardiomyopathy: what is needed to move to translation?How do mutations in contractile proteins cause the primary familial cardiomyopathies?Cardiomyopathy mutations reveal variable region of myosin converter as major element of cross-bridge compliance.CsmA, a class V chitin synthase with a myosin motor-like domain, is localized through direct interaction with the actin cytoskeleton in Aspergillus nidulansContractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function.The myosin C-loop is an allosteric actin contact sensor in actomyosinThe myosin cardiac loop participates functionally in the actomyosin interaction.
P2860
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P2860
Characterization of mutant myosins of Dictyostelium discoideum equivalent to human familial hypertrophic cardiomyopathy mutants. Molecular force level of mutant myosins may have a prognostic implication
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Characterization of mutant myo ...... have a prognostic implication
@en
Characterization of mutant myo ...... have a prognostic implication.
@nl
type
label
Characterization of mutant myo ...... have a prognostic implication
@en
Characterization of mutant myo ...... have a prognostic implication.
@nl
prefLabel
Characterization of mutant myo ...... have a prognostic implication
@en
Characterization of mutant myo ...... have a prognostic implication.
@nl
P2093
P2860
P356
P1476
Characterization of mutant myo ...... have a prognostic implication
@en
P2093
P2860
P304
P356
10.1172/JCI119228
P407
P577
1997-03-01T00:00:00Z