Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis. - Wikidata - awgldk - TriplyDB

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

http://www.wikidata.org/entity/Q39783590

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Wnt signaling pathway in non-small cell lung cancer The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair Correlation between the methylation of SULF2 and WRN promoter and the irinotecan chemosensitivity in gastric cancer High Energy Particle Radiation-associated Oncogenic Transformation in Normal Mice: Insight into the Connection between Activation of Oncotargets and Oncogene Addiction Glycogene expression alterations associated with pancreatic cancer epithelial-mesenchymal transition in complementary model systems Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration Substrate specificity of 6-O-endosulfatase (Sulf-2) and its implications in synthesizing anticoagulant heparan sulfate.Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers Oligosaccharide substrate preferences of human extracellular sulfatase Sulf2 using liquid chromatography-mass spectrometry based glycomics approaches.Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal model Modifications of glycans: biological significance and therapeutic opportunities MYCN-dependent expression of sulfatase-2 regulates neuroblastoma cell survival.Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis.Hypoxia negatively regulates heparan sulfatase 2 expression in renal cancer cell lines.Loss of corneal epithelial heparan sulfate leads to corneal degeneration and impaired wound healing.Application of a novel score test for genetic association incorporating gene-gene interaction suggests functionality for prostate cancer susceptibility regions.Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts.Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15.SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer.Novel therapeutic targets in the brain tumor microenvironment Silencing of HSulf-2 expression in MCF10DCIS.com cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo.Lung cancer: Biology and treatment options.SULF2 expression by immunohistochemistry and overall survival in oesophageal cancer: a cohort study.Role of heparan sulfatases in ovarian and breast cancer.Sulfatase 2 promotes breast cancer progression through regulating some tumor-related factors.Drosophila heparan sulfate 6-O-endosulfatase Sulf1 facilitates wingless (Wg) protein degradation The role of Drosophila heparan sulfate 6-O-endosulfatase in sulfation compensation.A role for PVRL4-driven cell-cell interactions in tumorigenesis.Overexpression of Sulf2 in idiopathic pulmonary fibrosis Proteoglycans and their roles in brain cancer.Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.Involvement of SULF2 in y-irradiation-induced invasion and resistance of cancer cells by inducing IL-6 expression.Impact of Sulfatase-2 on cancer progression and prognosis in patients with renal cell carcinoma.The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck Sulf-2: an extracellular modulator of cell signaling and a cancer target candidate.

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P2860

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

http://www.wikidata.org/entity/Q39783590

description

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2009年论文

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name

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

@en

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

@nl

type

label

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

@en

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

@nl

prefLabel

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

@en

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

@nl

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Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

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A van Zante

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P2860

Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival

Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation

Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans

Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue

Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling

Functional consequences of the subdomain organization of the sulfs

Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer.

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

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