A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival. - Wikidata - awgldk - TriplyDB

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.

http://www.wikidata.org/entity/Q39845869

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Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1 Molecular biology of lung cancer: clinical implications The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?The value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancers Genetics and biology of pancreatic ductal adenocarcinoma Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up Identification of aberrant pathways and network activities from high-throughput data Sheep, wolf, or werewolf: cancer stem cells and the epithelial-to-mesenchymal transition Non-coding RNAs in lung cancer EMT or EMT-Promoting Transcription Factors, Where to Focus the Light?Links between cancer stem cells and epithelial-mesenchymal transition KRAS as a Therapeutic Target Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling Identification of pyrazolopyridazinones as PDEδ inhibitors.Single Synonymous Mutations in KRAS Cause Transformed Phenotypes in NIH3T3 Cells Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.Targeting the RAS oncogene.Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers.A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer Somatic mutations in exocrine pancreatic tumors: association with patient survival FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.Prognostic value of the KRAS G12V mutation in 841 surgically resected Caucasian lung adenocarcinoma cases Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.RAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae A Pan-GTPase Inhibitor as a Molecular Probe Genomics and bioinformatics of Parkinson's disease MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas Ras history: The saga continues.Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells Reconstructing targetable pathways in lung cancer by integrating diverse omics data

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A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.

http://www.wikidata.org/entity/Q39845869

description

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A gene expression signature as ...... f EMT and tumor cell survival.

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A gene expression signature as ...... f EMT and tumor cell survival.

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A gene expression signature as ...... f EMT and tumor cell survival.

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A gene expression signature as ...... f EMT and tumor cell survival.

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Identifying biological themes within lists of genes with EASE

Cluster analysis and display of genome-wide expression patterns

Characterizing the cancer genome in lung adenocarcinoma.

Allele-specific amplification in cancer revealed by SNP array analysis

DAVID: Database for Annotation, Visualization, and Integrated Discovery

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays

ONCOMINE: a cancer microarray database and integrated data-mining platform

Structure and function of Syk protein-tyrosine kinase

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

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