Amide derivatives of ethacrynic acid: synthesis and evaluation as antagonists of Wnt/beta-catenin signaling and CLL cell survival.
about
Wnt/beta-catenin signaling and small molecule inhibitorsA Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent CancersPolyphenol Compound as a Transcription Factor InhibitorDevelopment of anticancer agents targeting the Wnt/β-catenin signalingEthacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway.Stat3 activates the receptor tyrosine kinase like orphan receptor-1 gene in chronic lymphocytic leukemia cells.Ethacrynic acid analogues lacking the alpha,beta-unsaturated carbonyl unit--potential anti-metastatic drugs.Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia.Large-scale analysis of DNA methylation in chronic lymphocytic leukemiaInhibitory effects of ethacrynic acid analogues lacking the α,β-unsaturated carbonyl unit and para-acylated phenols on human cancer cells.Pharmacophore modeling, 3D-QSAR and DFT studies of IWR small-molecule inhibitors of Wnt response.Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics.Investigations on dendrimer space reveal solid and liquid tumor growth-inhibition by original phosphorus-based dendrimers and the corresponding monomers and dendrons with ethacrynic acid motifs.Understanding and Targeting the Wnt/β-Catenin Signaling Pathway in Chronic Leukemia.Structure-activity relationship studies of small-molecule inhibitors of Wnt response.Inhibition of nuclear Wnt signalling: challenges of an elusive target for cancer therapy.
P2860
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P2860
Amide derivatives of ethacrynic acid: synthesis and evaluation as antagonists of Wnt/beta-catenin signaling and CLL cell survival.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Amide derivatives of ethacryni ...... gnaling and CLL cell survival.
@en
Amide derivatives of ethacryni ...... gnaling and CLL cell survival.
@nl
type
label
Amide derivatives of ethacryni ...... gnaling and CLL cell survival.
@en
Amide derivatives of ethacryni ...... gnaling and CLL cell survival.
@nl
prefLabel
Amide derivatives of ethacryni ...... gnaling and CLL cell survival.
@en
Amide derivatives of ethacryni ...... gnaling and CLL cell survival.
@nl
P2093
P2860
P1476
Amide derivatives of ethacryni ...... gnaling and CLL cell survival.
@en
P2093
Christina C N Wu
Dennis A Carson
Desheng Lu
Guangyi Jin
Howard B Cottam
Jerry X Liu
Shiyin Yao
P2860
P304
P356
10.1016/J.BMCL.2008.12.067
P407
P577
2008-12-24T00:00:00Z