BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3.
about
Regulation of Bim in Health and DiseaseConstitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancerApoptosis induction by MEK inhibition in human lung cancer cells is mediated by BimBim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway.An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737.Bim and VDAC1 are hierarchically essential for mitochondrial ATF2 mediated cell deathThe effect of BIM deletion polymorphism on intrinsic resistance and clinical outcome of cancer patient with kinase inhibitor therapy.Voltage-Dependent Anion Channel 1(VDAC1) Participates the Apoptosis of the Mitochondrial Dysfunction in Desminopathy.EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin.Bcl-2-enhanced efficacy of microtubule-targeting chemotherapy through Bim overexpression: implications for cancer treatment.BH3 profiling discriminates response to cytarabine-based treatment of acute myelogenous leukemiaApoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.Oridonin synergizes with Nutlin-3 in osteosarcoma cells by modulating the levels of multiple Bcl-2 family proteins.Preclinical and phase I results of decitabine in combination with midostaurin (PKC412) for newly diagnosed elderly or relapsed/refractory adult patients with acute myeloid leukemia.Irreversible pan-ERBB inhibitor canertinib elicits anti-leukaemic effects and induces the regression of FLT3-ITD transformed cells in mice.Expression profile of heat shock proteins in acute myeloid leukaemia patients reveals a distinct signature strongly associated with FLT3 mutation status--consequences and potentials for pharmacological intervention.
P2860
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P2860
BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
BH3-only protein Bim more crit ...... itors carrying oncogenic FLT3.
@en
BH3-only protein Bim more crit ...... itors carrying oncogenic FLT3.
@nl
type
label
BH3-only protein Bim more crit ...... itors carrying oncogenic FLT3.
@en
BH3-only protein Bim more crit ...... itors carrying oncogenic FLT3.
@nl
prefLabel
BH3-only protein Bim more crit ...... itors carrying oncogenic FLT3.
@en
BH3-only protein Bim more crit ...... itors carrying oncogenic FLT3.
@nl
P2093
P2860
P50
P1433
P1476
BH3-only protein Bim more crit ...... itors carrying oncogenic FLT3.
@en
P2093
Amanda Nordigården
Andreas Villunger
Maria Kraft
Pernilla Eliasson
P2860
P304
P356
10.1182/BLOOD-2008-07-167023
P407
P577
2008-12-08T00:00:00Z