Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells. - Wikidata - awgldk - TriplyDB

Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells.

Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells.

http://www.wikidata.org/entity/Q39907955

about

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma Transfection of a human glioblastoma cell line with liver-type glutaminase (LGA) down-regulates the expression of DNA-repair gene MGMT and sensitizes the cells to alkylating agents Silencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cells Targeting mitochondrial glutaminase activity inhibits oncogenic transformation.Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells.Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2 Understanding the non-canonical pathways involved in p53-mediated tumor suppression.Metabolic regulation by p53.Mammalian glutaminase isozymes in brain.Therapeutic strategies impacting cancer cell glutamine metabolism.How does cancer cell metabolism affect tumor migration and invasion?Brain glutaminases.Gene set enrichment analysis of the NF-κB/Snail/YY1/RKIP circuitry in multiple myeloma.Glutamine at focus: versatile roles in cancer.A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis.p63 regulates glutaminase 2 expression.Glutamine Addiction In Gliomas.Glutaminase 2 expression is associated with regional heterogeneity of 5-aminolevulinic acid fluorescence in glioblastoma.Glutamine Metabolism in Gliomas.Glutaminases.Expression of Gls and Gls2 glutaminase isoforms in astrocytes.Downregulation of GLS2 in glioblastoma cells is related to DNA hypermethylation but not to the p53 status.

P2860

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P2860

Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells.

http://www.wikidata.org/entity/Q39907955

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

Transfection with liver-type g ...... feration of T98G glioma cells.

@en

Transfection with liver-type g ...... feration of T98G glioma cells.

@nl

type

label

Transfection with liver-type g ...... feration of T98G glioma cells.

@en

Transfection with liver-type g ...... feration of T98G glioma cells.

@nl

prefLabel

Transfection with liver-type g ...... feration of T98G glioma cells.

@en

Transfection with liver-type g ...... feration of T98G glioma cells.

@nl

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Transfection with liver-type g ...... iferation of T98G glioma cells

@en

P2093

Carolina Lobo

http://www.w3.org/2001/XMLSchema#string

Ewa Matyja

http://www.w3.org/2001/XMLSchema#string

Francisco J Alonso

http://www.w3.org/2001/XMLSchema#string

Marzena Łazarczyk

http://www.w3.org/2001/XMLSchema#string

Monika Szeliga

http://www.w3.org/2001/XMLSchema#string

Wojciech Hilgier

http://www.w3.org/2001/XMLSchema#string

P2860

The calpain system as a modulator of stress/damage response

Differentiation between high- and low-grade astrocytoma using a human recombinant antibody to the extra domain-B of fibronectin.

Glutaminase: a multifaceted protein not only involved in generating glutamate.

MGMT methylation status: the advent of stratified therapy in glioblastoma?

P304

1014-1023

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scholarly article

P356

10.1002/GLIA.20825

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9

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57

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Marta Obara-Michlewska

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2009-07-01T00:00:00Z

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19062176

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