Notch signaling is required for exocrine regeneration after acute pancreatitis.
about
Alcoholic pancreatitis: New insights into the pathogenesis and treatmentNotch Signaling in Pancreatic DevelopmentGenetically engineered mouse models of pancreatic adenocarcinomaControl of cell identity in pancreas development and regenerationSilencing Mist1 Gene Expression Is Essential for Recovery from Acute PancreatitisTherapeutic potential of targeting acinar cell reprogramming in pancreatic cancerNotch1 represses osteogenic pathways in aortic valve cellsDll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processesEMT and dissemination precede pancreatic tumor formationBeta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice.Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo.KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.Aberrant innate immune activation following tissue injury impairs pancreatic regeneration.EZH2 couples pancreatic regeneration to neoplastic progression.Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinomaAcute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.Pancreatic beta-cells: from generation to regeneration.Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinomaContext-dependent transformation of adult pancreatic cells by oncogenic K-Ras.Molecular characteristics of pancreatic ductal adenocarcinomaStat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.Epithelial Notch signaling is a limiting step for pancreatic carcinogenesis.The jagged-2/notch-1/hes-1 pathway is involved in intestinal epithelium regeneration after intestinal ischemia-reperfusion injuryRegeneration and repair of the exocrine pancreas.Dicer regulates differentiation and viability during mouse pancreatic cancer initiationβ-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice.K-Ras and cyclooxygenase-2 coactivation augments intraductal papillary mucinous neoplasm and Notch1 mimicking human pancreas lesions.Ethanol administration impairs pancreatic repair after injury.Bmi1 is required for regeneration of the exocrine pancreas in miceValproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation ProgramsThe Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer.Hippo signaling regulates differentiation and maintenance in the exocrine pancreasEarly pancreatic islet fate and maturation is controlled through RBP-JκNotch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasiaPancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia.gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease.Molecular basis for pancreatitis.Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasisMolecular and cellular regulation of pancreatic acinar cell function.
P2860
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P2860
Notch signaling is required for exocrine regeneration after acute pancreatitis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Notch signaling is required for exocrine regeneration after acute pancreatitis.
@en
type
label
Notch signaling is required for exocrine regeneration after acute pancreatitis.
@en
prefLabel
Notch signaling is required for exocrine regeneration after acute pancreatitis.
@en
P2093
P50
P1433
P1476
Notch signaling is required for exocrine regeneration after acute pancreatitis
@en
P2093
Hassan Nakhai
Jens T Siveke
Marcel Lee
Roland M Schmid
P304
P356
10.1053/J.GASTRO.2007.11.003
P407
P577
2007-11-04T00:00:00Z