beta-arrestin-biased agonism at the beta2-adrenergic receptor.
about
Non-Coding RNAs Regulating Morphine Function: With Emphasis on the In vivo and In vitro Functions of miR-190Carboxy-terminus of CXCR7 regulates receptor localization and functionNovel endogenous peptide agonists of cannabinoid receptorsbeta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in miceTargeting G protein coupled receptor-related pathways as emerging molecular therapiesPotential benefits of therapeutic use of β2-adrenergic receptor agonists in neuroprotection and Parkinsonμs diseaseReceptor heteromerization expands the repertoire of cannabinoid signaling in rodent neuronsGenetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and CarvedilolMolecular mechanisms underlying β-adrenergic receptor-mediated cross-talk between sympathetic neurons and immune cellsExtracellular ubiquitin: immune modulator and endogenous opponent of damage-associated molecular pattern moleculesQuantitative modeling of GRK-mediated beta2AR regulationG-Protein/β-Arrestin-Linked Fluctuating Network of G-Protein-Coupled Receptors for Predicting Drug Efficacy and Bias Using Short-Term Molecular Dynamics SimulationIndependent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptorCyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart{Beta}-blocker drugs mediate calcium signaling in native central nervous system neurons by {beta}-arrestin-biased agonismThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsAgonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2Simulations of biased agonists in the β(2) adrenergic receptor with accelerated molecular dynamics.Optodynamic simulation of β-adrenergic receptor signalling.Divergent label-free cell phenotypic pharmacology of ligands at the overexpressed β₂-adrenergic receptors.Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptorsGPR54 regulates ERK1/2 activity and hypothalamic gene expression in a Gα(q/11) and β-arrestin-dependent manner.Ligand-directed signalling at beta-adrenoceptorsPartially deglycosylated equine LH preferentially activates beta-arrestin-dependent signaling at the follicle-stimulating hormone receptor.Internalization dissociates β2-adrenergic receptorsSex differences in stress-related psychiatric disorders: neurobiological perspectives.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Beyond desensitization: physiological relevance of arrestin-dependent signaling.Crosstalk between beta-2-adrenoceptor and muscarinic acetylcholine receptors in the airwayLigand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling.Teaching old receptors new tricks: biasing seven-transmembrane receptors.Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanineFunctional selectivity in adrenergic and angiotensin signaling systems.Natriuretic hormones, endogenous ouabain, and related sodium transport inhibitors.Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure.Exploring a role for heteromerization in GPCR signalling specificity.β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration.Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.Dissociations in the effects of β2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: support for the concept of functional selectivity.
P2860
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P2860
beta-arrestin-biased agonism at the beta2-adrenergic receptor.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
beta-arrestin-biased agonism at the beta2-adrenergic receptor.
@en
type
label
beta-arrestin-biased agonism at the beta2-adrenergic receptor.
@en
prefLabel
beta-arrestin-biased agonism at the beta2-adrenergic receptor.
@en
P2093
P356
P1476
beta-arrestin-biased agonism at the beta2-adrenergic receptor.
@en
P2093
Erin J Whalen
James W Wisler
Jonathan D Violin
Matthew T Drake
Robert J Lefkowitz
Sudha K Shenoy
P304
P356
10.1074/JBC.M708118200
P407
P577
2007-12-17T00:00:00Z