Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents.
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The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic TargetNOX3 NADPH oxidase couples transient receptor potential vanilloid 1 to signal transducer and activator of transcription 1-mediated inflammation and hearing lossStat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1Induction of interferon-stimulated genes by Simian virus 40 T antigens.Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damageTranscriptional role of p53 in interferon-mediated antiviral immunity.Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription.Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance.Proteomic profile of KSR1-regulated signalling in response to genotoxic agents in breast cancer.STAT1 Activation Is Enhanced by Cisplatin and Variably Affected by EGFR Inhibition in HNSCC CellsSmall-interfering RNA-mediated silencing of the MAPK p42 gene induces dual effects in HeLa cells.Combination treatment in vitro with Nutlin, a small-molecule antagonist of MDM2, and pegylated interferon-α 2a specifically targets JAK2V617F-positive polycythemia vera cellsGamma-radiation (GR) triggers a unique gene expression profile associated with cell death compared to proton radiation (PR) in mice in vivo.Wedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation.Interferon-inducible Ifi200-family genes in systemic lupus erythematosusPannexin 1 involvement in bladder dysfunction in a multiple sclerosis model.Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α.Cisplatin-induced hair cell death requires STAT1 and is attenuated by epigallocatechin gallate.Emerging roles of p53 and other tumour-suppressor genes in immune regulationCellular response to alkylating agent MNNG is impaired in STAT1-deficients cells.The human papillomavirus E7 oncoprotein as a regulator of transcription.Elevated levels of STAT1 in Fanconi anemia group A lymphoblasts correlate with the cells' sensitivity to DNA interstrand crosslinking drugs.The inhibiting effect of the transcription factor p53 on dengue virus infection by activating the type I interferon.The Interaction Between Human Papillomaviruses and the Stromal Microenvironment.IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice.
P2860
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P2860
Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Identification of a novel p53- ...... y antitumour genotoxic agents.
@en
type
label
Identification of a novel p53- ...... y antitumour genotoxic agents.
@en
prefLabel
Identification of a novel p53- ...... y antitumour genotoxic agents.
@en
P2093
P2860
P356
P1476
Identification of a novel p53- ...... y antitumour genotoxic agents.
@en
P2093
C Le Clorennec
F Baran-Marszak
G W Bornkamm
I Youlyouz-Marfak
J Feuillard
L Reminieras
P2860
P2888
P304
P356
10.1038/SJ.CDD.4402270
P577
2007-11-09T00:00:00Z
P5875
P6179
1012219103