Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation.
about
p53 acetylation is crucial for its transcription-independent proapoptotic functionsDeletion of Ku70, Ku80, or both causes early aging without substantially increased cancerSirtuin 1 and sirtuin 3: physiological modulators of metabolismOpposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activityThe peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Sirt1 is involved in energy metabolism: the role of chronic ethanol feeding and resveratrol.Cyclin-C-dependent cell-cycle entry is required for activation of non-homologous end joining DNA repair in postmitotic neuronsThe C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor.Neuroprotective and metabolic effects of resveratrol: therapeutic implications for Huntington's disease and other neurodegenerative disorders.Cell-Penetrating Penta-Peptides (CPP5s): Measurement of Cell Entry and Protein-Transduction ActivityHigh levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients.Histone deacetylase inhibitors sensitize lung cancer cells to hyperthermia: involvement of Ku70/SirT-1 in thermo-protectionBax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases.Cell-Penetrating Peptides Selectively Cross the Blood-Brain Barrier In Vivo.Prognostic and clinical value of Sirt1 expression in gastric cancer: A systematic meta-analysis.Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicityRegulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation.Bax-induced apoptosis shortens the life span of DNA repair defect Ku70-knockout mice by inducing emphysemaInvolvement of all-trans-retinal in acute light-induced retinopathy of mice.Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis.Reactivation of p53 by novel MDM2 inhibitors: implications for pancreatic cancer therapy.The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy.Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A researchCurrent understanding on the pathogenesis of polyglutamine diseases.Modifiers and mechanisms of multi-system polyglutamine neurodegenerative disorders: lessons from fly models.Bioportides: bioactive cell-penetrating peptides that modulate cellular dynamics.SIRT1 regulation modulates stroke outcome.Determinants of eosinophil survival and apoptotic cell death.SIRT1 promotes the proliferation and metastasis of human pancreatic cancer cells.SIRT1 knockdown promotes neural differentiation and attenuates the heat shock response.Expression patterns and potential roles of SIRT1 in human medulloblastoma cells in vivo and in vitro.Resveratrol induces gastric cancer cell apoptosis via reactive oxygen species, but independent of sirtuin1.SIRT1 RNAi knockdown induces apoptosis and senescence, inhibits invasion and enhances chemosensitivity in pancreatic cancer cells.Cell-penetrating penta-peptides and Bax-inhibiting peptides: protocol for their application.Sirtuin modulators control reactive gliosis in an in vitro model of Alzheimer's disease.Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.Treatment with Caffeic Acid and Resveratrol Alleviates Oxidative Stress Induced Neurotoxicity in Cell and Drosophila Models of Spinocerebellar Ataxia Type3.Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis.
P2860
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P2860
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Bax-inhibiting peptide protect ...... ty caused by Ku70 acetylation.
@en
type
label
Bax-inhibiting peptide protect ...... ty caused by Ku70 acetylation.
@en
prefLabel
Bax-inhibiting peptide protect ...... ty caused by Ku70 acetylation.
@en
P2093
P356
P1476
Bax-inhibiting peptide protect ...... ty caused by Ku70 acetylation.
@en
P2093
H Mizusawa
H Sasaguri
K Ishikawa
S Matsuyama
P2888
P304
P356
10.1038/SJ.CDD.4402219
P577
2007-09-21T00:00:00Z
P5875
P6179
1009463768