Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.
about
Dopamine D2 receptors form higher order oligomers at physiological expression levelsMarked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptorsCell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerizationInvestigation of allosteric modulation mechanism of metabotropic glutamate receptor 1 by molecular dynamics simulations, free energy and weak interaction analysisStructural Role of the Terminal Disulfide Bond in the Sweetness of BrazzeinTrans-activation between 7TM domains: implication in heterodimeric GABAB receptor activationMechanisms of multimodal sensing by extracellular Ca(2+)-sensing receptors: a domain-based survey of requirements for binding and signallingStructure and ligand recognition of class C GPCRsKey amino acid residues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1R3 human sweet receptor.BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues.Homeostatic scaling requires group I mGluR activation mediated by Homer1a.G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.Lighting up multiprotein complexes: lessons from GPCR oligomerizationStoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: molecular modeling and experimental validation.Interdomain movements in metabotropic glutamate receptor activation.The significance of G protein-coupled receptor crystallography for drug discovery.Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors.Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptorsSensing conformational changes in metabotropic glutamate receptors.Molecular mechanism for the umami taste synergism.Generation of human PTH1R construct with FLAG epitope located internally: comparison of two-fragment assembly by using PCR overlap extension or ligase.Peripheral mechanisms of pain and analgesia.A cell surface inactive mutant of the human lutropin receptor (hLHR) attenuates signaling of wild-type or constitutively active receptors via heterodimerization.Molecular basis for amino acid sensing by family C G-protein-coupled receptors.Structural determinants underlying constitutive dimerization of unoccupied human follitropin receptors.Group II metabotropic glutamate receptors and schizophrenia.G-protein-coupled receptor oligomers: two or more for what? Lessons from mGlu and GABAB receptors.HTRF: A technology tailored for drug discovery - a review of theoretical aspects and recent applications.On the expanding terminology in the GPCR field: the meaning of receptor mosaics and receptor heteromers.Progress toward advanced understanding of metabotropic glutamate receptors: structure, signaling and therapeutic indicationsUnderstanding the added value of g-protein-coupled receptor heteromers.Structure and function of G protein-coupled receptor oligomers: implications for drug discovery.Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopyAllosteric communication between protomers of dopamine class A GPCR dimers modulates activation.G protein activation by the leukotriene B4 receptor dimer. Evidence for an absence of trans-activation.Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.Comparative fluorescence resonance energy transfer analysis of metabotropic glutamate receptors: implications about the dimeric arrangement and rearrangement upon ligand bindings.
P2860
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P2860
Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.
@en
type
label
Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.
@en
prefLabel
Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.
@en
P2093
P356
P1476
Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement
@en
P2093
Carsten Brock
Laure Boudier
Nadia Oueslati
Stéphan Soler
P304
33000-33008
P356
10.1074/JBC.M702542200
P407
P577
2007-09-13T00:00:00Z