Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates.
about
Polo-like kinase 4: the odd one out of the familyWhen the genome plays dice: circumvention of the spindle assembly checkpoint and near-random chromosome segregation in multipolar cancer cell mitosesCep76, a centrosomal protein that specifically restrains centriole reduplicationAb ovo or de novo? Mechanisms of centriole duplicationPutting a bit into the polo-box domain of polo-like kinase 1A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering.Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach.Control of daughter centriole formation by the pericentriolar material.Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability.Autophosphorylation of polo-like kinase 4 and its role in centriole duplicationPolo-box domain: a versatile mediator of polo-like kinase function.Control of centrin stability by Aurora A.A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention.Centrosome biogenesis continues in the absence of microtubules during prolonged S-phase arrest.Daughter centriole elongation is controlled by proteolysisA centrosome-autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage.Centriole duplication: A lesson in self-control.Genomic instability and cancer: lessons learned from human papillomaviruses.Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication.A clinical overview of centrosome amplification in human cancers.Centrosome abnormalities during a Chlamydia trachomatis infection are caused by dysregulation of the normal duplication pathway.Functional relationship among PLK2, PLK4 and ROCK2 to induce centrosome amplification.Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16INK4a deficiency and telomere-dependent genotoxic stressAnalysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasmsImpaired p53 function leads to centrosome amplification, acquired ERalpha phenotypic heterogeneity and distant metastases in breast cancer MCF-7 xenografts.PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigenStem cells, phenotypic inversion, and differentiation.The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication.Oncogenic activities of human papillomaviruses.The human papillomavirus E7 oncoprotein.Viral transformation and aneuploidy.The life cycle of centriolesSuch small hands: the roles of centrins/caltractins in the centriole and in genome maintenance.Show me your license, please: deregulation of centriole duplication mechanisms that promote amplification.Manipulation of cellular DNA damage repair machinery facilitates propagation of human papillomaviruses.Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues.Ubiquitin, the centrosome, and chromosome segregation.SKA1 over-expression promotes centriole over-duplication, centrosome amplification and prostate tumourigenesis.CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancerFM19G11: A new modulator of HIF that links mTOR activation with the DNA damage checkpoint pathways.
P2860
Q21203551-F527A04B-987F-4C84-8413-5292E885FD2FQ21562294-B9B3C4C5-66DA-44E4-8B23-5F1018A37970Q24312709-0AE7B405-21B0-48E9-A906-20832E889606Q24650428-FE6E3AAF-9040-4BE7-A926-4D9EB10E41C9Q26779135-94A7FA29-6C67-49E7-8660-B5B6AD31CBC6Q30502330-BA4558EF-B4BF-4A9F-AF2B-76C0BEFD8EFEQ30523067-32E9559D-78C5-4652-A220-C64975AC7836Q33320973-FA367FEC-4876-41D0-9FDD-1F331C433A64Q33618895-6D8FB006-68E8-4188-83F4-F4313BA16812Q33647010-80FB0F44-0381-402C-B265-B2A956DF0863Q33882148-832A9AD2-3DE2-4CDB-9AE4-C0B0E21C3ADBQ33952284-DE39BA0A-DA54-466B-A86D-F7E174F9EDBBQ33968462-4466E728-25E2-4773-A352-4FF32A329BD0Q34091715-068692F8-D5BC-4251-ABE1-3DA859A31FDAQ34313464-1A402924-697E-4C20-A75F-7CAC904E0F19Q34313511-F672AA66-60F0-4FD1-94E1-BEEA1D421914Q34582145-414AB5D1-1215-418E-A5AB-4448348F2F82Q34612265-04D280AF-A450-4785-AF83-0BFCE2100C88Q34776015-342C49EC-3A63-4C4C-A5BB-650C1C09ECD0Q35479894-AA87BC0D-784F-491D-BB4C-8830D6BC075CQ35841813-ADDB7F5D-999D-4261-914B-A43585EE2221Q36187901-83EA2F51-8C9F-4252-B18F-416815F5C2EEQ36414032-94F505F8-772E-406F-B892-AA81FE5DF869Q36496306-49CAB4EF-D1B0-4FA1-A9CC-6539C4673BA3Q36852947-38311A12-1A4E-4C5F-A932-644640E55B0FQ36954633-904EE35B-5C6E-428F-A245-ABA83A658511Q37000173-A414E04C-85A9-443C-BDB5-5F26004EB9FCQ37124885-7B06E9C5-76CB-46F7-8580-2845EE47F12AQ37316158-CAC70867-6FBA-45B1-89D9-F2C8EFFD406AQ37325199-71FED292-62EB-416A-A9A3-14B08B9AE323Q37384276-897F7E7E-82B6-48D7-B238-567F70D40BA4Q37627202-2E12F28E-FE17-4356-BA74-B80D6229BC5CQ37998379-D852F80E-7A33-486E-ADC3-8B92A8A37FA8Q38034629-91152670-1C00-4191-B668-4B56D53F2B7EQ38177526-DBE863FB-4E35-4DAD-A59F-94346401A6A7Q38662334-A0AF056C-4A9E-43FE-87C5-1E57BC2A91BBQ38678006-94E3B651-8994-4339-9777-1AC60E72222AQ38995104-03CCC5FB-C0B3-499A-AA61-E810B814F3E7Q39270008-D1E15AE2-A91D-41E4-8567-5420EAF34DA3Q39672963-0F49CD55-9397-49F4-A511-41C3B7DFF13B
P2860
Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Centriole overduplication thro ...... at single maternal templates.
@en
type
label
Centriole overduplication thro ...... at single maternal templates.
@en
prefLabel
Centriole overduplication thro ...... at single maternal templates.
@en
P2093
P2860
P356
P1433
P1476
Centriole overduplication thro ...... at single maternal templates.
@en
P2093
A Duensing
J Kleylein-Sohn
S A Perdreau
S Duensing
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210456
P407
P577
2007-04-16T00:00:00Z
P5875
P6179
1035649135