A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth.
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NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membraneThe PTEN tumor suppressor gene and its role in lymphoma pathogenesisFocus on PTEN RegulationBalancing Proliferation and Connectivity in PTEN-associated Autism Spectrum DisorderA phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppressionA functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activityEngineering ePTEN, an enhanced PTEN with increased tumor suppressor activities.Different conformations of phosphatase and tensin homolog, deleted on chromosome 10 (PTEN) protein within the nucleus and cytoplasm of neuronsPTEN Tumor Suppressor Network in PI3K-Akt Pathway ControlNOA36 protein contains a highly conserved nucleolar localization signal capable of directing functional proteins to the nucleolus, in mammalian cellsAMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressorA novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localizationControlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential.Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium.Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cellsDissecting the cell to nucleus, perinucleus and cytosol.A unified nomenclature and amino acid numbering for human PTEN.Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.The APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisFine-Tuning of Pten Localization and Phosphatase Activity Is Essential for Zebrafish Angiogenesis.Cytoplasmic PTEN protein loss distinguishes intraductal carcinoma of the prostate from high-grade prostatic intraepithelial neoplasia.Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation.ATP modulates PTEN subcellular localization in multiple cancer cell lines.Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis.ΔNp63α represses nuclear translocation of PTEN by inhibition of NEDD4-1 in keratinocytes.Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function.Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells.Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity.RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors.Study of PTEN subcellular localization.Engineering PTEN function: membrane association and activity.PTEN genomic deletion defines favorable prognostic biomarkers in localized prostate cancer: a systematic review and meta-analysis.Oncogenic PTEN functions and models in T-cell malignancies.PTEN activation through K163 acetylation by inhibiting HDAC6 contributes to tumour inhibition.A new class of cancer-associated PTEN mutations defined by membrane translocation defects.Phosphatase and Tensin Homolog Is a Growth Repressor of Both Rhizoid and Gametophore Development in the Moss Physcomitrella patens.Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN.A motor driving PTEN.PTEN/PTENP1: 'Regulating the regulator of RTK-dependent PI3K/Akt signalling', new targets for cancer therapy.
P2860
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P2860
A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A short N-terminal sequence of ...... or suppression of cell growth.
@en
type
label
A short N-terminal sequence of ...... or suppression of cell growth.
@en
prefLabel
A short N-terminal sequence of ...... or suppression of cell growth.
@en
P2093
P2860
P356
P1433
P1476
A short N-terminal sequence of ...... or suppression of cell growth.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210175
P407
P577
2007-01-08T00:00:00Z
P5875
P6179
1046852045