AID-dependent histone acetylation is detected in immunoglobulin S regions.
about
Epigenetics of Peripheral B-Cell Differentiation and the Antibody ResponseTranscriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrityAID targeting is dependent on RNA polymerase II pausing.Chromatin structure regulates gene conversion.ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.High resolution analysis of the chromatin landscape of the IgE switch region in human B cellsRegulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.AID and somatic hypermutation.Roles for histone H3K4 methyltransferase activities during immunoglobulin class-switch recombinationAID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.The AID-induced DNA damage response in chromatin.Mechanism and regulation of class switch recombinationEpigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.Mismatch-mediated error prone repair at the immunoglobulin genes.Nucleotide excision repair in an immunoglobulin variable gene is less efficient than in a housekeeping gene.Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations.AIDing antibody diversity by error-prone mismatch repair.Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation.DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination.Three-dimensional architecture of the IgH locus facilitates class switch recombination.Immunoglobulin class-switch DNA recombination: induction, targeting and beyond.Identification of core DNA elements that target somatic hypermutation.Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locusEpigenetics of the antibody responseH3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination.E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells.S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.AID hits the jackpot when missing the target.Switch region identity plays an important role in Ig class switch recombination.NF-kappa B binds to the immunoglobulin S gamma 3 region in vivo during class switch recombination.Single nucleotide changes in the human Igamma1 and Igamma4 promoters underlie different transcriptional responses to CD40.Ikaros controls isotype selection during immunoglobulin class switch recombination.S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombinationCombinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination.Activation of the Ig Iα1 promoter by the transcription factor Ets-1 triggers Ig Iα1-Cα1 germline transcription in epithelial cancer cellsUbiquitination events that regulate recombination of immunoglobulin Loci gene segments.Dissecting Epigenetic Dysregulation of Primary Antibody Deficiencies.Epigenetic regulation of immune checkpoints: another target for cancer immunotherapy?Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites.Physiological Roles of DNA Double-Strand Breaks.
P2860
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P2860
AID-dependent histone acetylation is detected in immunoglobulin S regions.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
AID-dependent histone acetylation is detected in immunoglobulin S regions.
@en
type
label
AID-dependent histone acetylation is detected in immunoglobulin S regions.
@en
prefLabel
AID-dependent histone acetylation is detected in immunoglobulin S regions.
@en
P2093
P2860
P356
P1476
AID-dependent histone acetylation is detected in immunoglobulin S regions.
@en
P2093
Amy L Kenter
Naree Whang
Robert Wuerffel
P2860
P304
P356
10.1084/JEM.20051774
P407
P577
2006-01-17T00:00:00Z