Chromosomal instability induced by Pim-1 is passage-dependent and associated with dysregulation of cyclin B1.
about
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersPim1 kinase synergizes with c-MYC to induce advanced prostate carcinomaMicroarray analysis in pulmonary hypertensionNUP98 dysregulation in myeloid leukemogenesisInteractions between cells with distinct mutations in c-MYC and Pten in prostate cancer.A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells.Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity.CamKII inhibitors reduce mitotic instability, connexon anomalies and progression of the in vivo behavioral phenotype in transgenic animals expressing a mutated Gjb1 gene.RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibitionERG deregulation induces PIM1 over-expression and aneuploidy in prostate epithelial cells.Regulation of Skp2 levels by the Pim-1 protein kinaseTumorigenic polyploid cells contain elevated ROS and ARE selectively targeted by antioxidant treatment.DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway.RAMP1 is a direct NKX3.1 target gene up-regulated in prostate cancer that promotes tumorigenesis.Why target PIM1 for cancer diagnosis and treatment?p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinaseThe Novel PIM1 Inhibitor NMS-P645 Reverses PIM1-Dependent Effects on TMPRSS2/ERG Positive Prostate Cancer Cells And Shows Anti-Proliferative Activity in Combination with PI3K Inhibition.MicroRNA-486-5p targeting PIM-1 suppresses cell proliferation in breast cancer cells.
P2860
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P2860
Chromosomal instability induced by Pim-1 is passage-dependent and associated with dysregulation of cyclin B1.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Chromosomal instability induce ...... th dysregulation of cyclin B1.
@en
type
label
Chromosomal instability induce ...... th dysregulation of cyclin B1.
@en
prefLabel
Chromosomal instability induce ...... th dysregulation of cyclin B1.
@en
P2093
P2860
P356
P1476
Chromosomal instability induce ...... th dysregulation of cyclin B1.
@en
P2093
Chisu Song
Jongchan Kim
Meejeon Roh
Sarki A Abdulkadir
P2860
P304
40568-40577
P356
10.1074/JBC.M509369200
P407
P577
2005-10-12T00:00:00Z