A proteolytic fragment of Mcl-1 exhibits nuclear localization and regulates cell growth by interaction with Cdk1.
about
Prevention of cytokine withdrawal-induced apoptosis by Mcl-1 requires interaction between Mcl-1 and BimATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage responseBID binds to replication protein A and stimulates ATR function following replicative stressMtd/Bok takes a swing: proapoptotic Mtd/Bok regulates trophoblast cell proliferation during human placental development and in preeclampsiaThr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancerGLTSCR2/PICT-1, a putative tumor suppressor gene product, induces the nucleolar targeting of the Kaposi's sarcoma-associated herpesvirus KS-Bcl-2 protein.Bim nuclear translocation and inactivation by viral interferon regulatory factor.GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria.Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1.MCL-1 localizes to sites of DNA damage and regulates DNA damage responseMyeloid cell leukemia-1 is associated with tumor progression by inhibiting apoptosis and enhancing angiogenesis in colorectal cancer.Obatoclax potentiates the cytotoxic effect of cytarabine on acute myeloid leukemia cells by enhancing DNA damage.DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosisCharacterization of multiple light damage paradigms reveals regional differences in photoreceptor loss.MCL-1 Depletion Impairs DNA Double-Strand Break Repair and Reinitiation of Stalled DNA Replication Forks.Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosis in human tumor cells.Leishmania donovani Exploits Myeloid Cell Leukemia 1 (MCL-1) Protein to Prevent Mitochondria-dependent Host Cell Apoptosis.Bcl-xL is an oncogenic driver in colorectal cancer.Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells.Revisiting the role of MCL1 in tumorigenesis of solid cancer: gene expression correlates with antiproliferative phenotype in breast cancer cells and its functional regulatory variants are associated with reduced cancer susceptibility.Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma.A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration.Mcl-1 functions as major epidermal survival protein required for proper keratinocyte differentiation.Gamma irradiation of human leukaemic cells HL-60 and MOLT-4 induces decrease in Mcl-1 and Bid, release of cytochrome c, and activation of caspase-8 and caspase-9.An essential role for MCL-1 in ATR-mediated CHK1 phosphorylationAssociation of anti-apoptotic Mcl-1L isoform expression with radioresistance of oral squamous carcinoma cells.Mcl-1 protects prostate cancer cells from cell death mediated by chemotherapy-induced DNA damage.Phospho-Bcl-x(L)(Ser62) plays a key role at DNA damage-induced G(2) checkpoint.Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage.Mcl-1 suppresses abasic site repair following bile acid-induced hepatic cellular DNA damage.The prognostic significance of MCL1 copy number gain in esophageal squamous cell carcinoma.Functional regulatory variants of MCL1 contribute to enhanced promoter activity and reduced risk of lung cancer in nonsmokers: implications for context-dependent phenotype of an antiapoptotic and antiproliferative gene in solid tumor.Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion.The N terminus of the anti-apoptotic BCL-2 homologue MCL-1 regulates its localization and function.Simultaneous targeting of ATM and Mcl-1 increases cisplatin sensitivity of cisplatin-resistant non-small cell lung cancer.Regulation of neutrophil survival/apoptosis by Mcl-1.
P2860
Q24301935-2938F97D-5C2D-43FF-90E6-319D7825CEACQ24312475-FCA4AC9C-76CD-4CC3-9C9B-F74FEBDDADECQ24631191-D88452E4-215D-4488-A09A-D8D6D8B0795DQ28119158-3A81EEC1-E424-4DF0-8F03-4CCC4EA9F1D5Q28484291-135509C0-32BD-4B9C-978A-53125AA52C0AQ30090237-E9470301-E130-45E9-A9EE-B8F38EB99F4FQ34047415-542275A6-B815-4073-BB18-F6052A631761Q34153147-CCA5FEE3-C598-46D2-B6B8-3C0A3F345D3CQ34425246-E5F6CA80-F4F6-4429-B3B6-3D3333674438Q34582160-FED1EBB6-1C24-49E1-8503-FD4F9D888FAEQ34991284-78FAE178-AE89-404C-965D-5C035747CAACQ35007971-401DCEEF-ABE9-4265-8BFB-EBDC401D402DQ35815150-4BF4B761-2AB1-4397-B851-988AC5BA2533Q35898077-C58C47EE-7761-4113-BA4C-0648BCCEC57AQ36184998-F757325F-7666-4EA4-9B22-6134C7A3A81CQ36526103-716DB4AA-92DA-48B2-A5BD-872482A2C90EQ36574003-87430BA9-9EA3-440E-8676-125A4BAAD901Q37412492-17563655-D18E-42C9-ADE2-9C5130389D9DQ37725415-57A9AC38-5D8B-4143-B27B-C1AF1CB2E227Q38992736-88E38DA8-9DA8-46AB-BD8E-28796D2BA630Q39080709-7B1E46FB-BEA6-43F2-A0C1-10EDF7AA5C82Q39122729-58C996B1-ABE3-4758-809F-8A3F803DB69AQ39911680-062704FD-49AC-4757-8ED3-102A2742A7A4Q39983630-F5800070-4D04-4961-B00B-BC717BFF4FE5Q41067688-C859217E-3A1F-4F81-94F6-4D1024C99D0AQ41531941-A2BE98FA-31A4-47AE-88EB-3DE1519CC78EQ41845149-B678742E-FA51-464D-B28C-91A97DC3E417Q41959713-78C58360-CEE1-4524-B082-CF4CFF5CF0C1Q43128865-D0B685F7-3F34-4120-89C7-DE3245E4B45EQ46339972-11450A4C-2B7F-4AB9-9E0A-A74D39CA29BDQ46922752-2D91D048-1C29-43C4-A72A-5861FF3D0295Q47269354-83CBCFC5-EAF7-45FE-BD13-A58822B276FAQ47373137-011C6DD1-C77B-43AF-91EB-0C671BCA6338Q53127485-8E446F8C-C247-4E0B-BE1C-114AB783EE6BQ53733720-E58EC414-D7D7-4534-B054-3DFB73C1CE6EQ54546811-0D1B7A32-2C4F-4624-854F-915798E1CFD4
P2860
A proteolytic fragment of Mcl-1 exhibits nuclear localization and regulates cell growth by interaction with Cdk1.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
A proteolytic fragment of Mcl- ...... owth by interaction with Cdk1.
@en
type
label
A proteolytic fragment of Mcl- ...... owth by interaction with Cdk1.
@en
prefLabel
A proteolytic fragment of Mcl- ...... owth by interaction with Cdk1.
@en
P2093
P2860
P356
P1433
P1476
A proteolytic fragment of Mcl- ...... owth by interaction with Cdk1.
@en
P2093
Juergen Kast
Payman Hojabrpour
Rafat Sobouti
Sarwat Jamil
Vincent Duronio
P2860
P304
P356
10.1042/BJ20041596
P407
P577
2005-05-01T00:00:00Z