Molecular definition of predictive indicators of stable protein expression in recombinant NS0 myeloma cells.
about
Optimized signal peptides for the development of high expressing CHO cell linesIntraclonal protein expression heterogeneity in recombinant CHO cellsProduction of recombinant protein therapeutics in cultivated mammalian cells.Using molecular markers to characterize productivity in Chinese hamster ovary cell lines.Towards the molecular characterization of the stable producer phenotype of recombinant antibody-producing NS0 myeloma cells.Identifying bottlenecks in transient and stable production of recombinant monoclonal-antibody sequence variants in Chinese hamster ovary cellsEvaluating the use of a CpG free promoter for long-term recombinant protein expression stability in Chinese hamster ovary cells.Evaluating the expression profile and stability of different UCOE containing vector combinations in mAb-producing CHO cellsUsing cell engineering and omic tools for the improvement of cell culture processes.Improved antibody production in Chinese hamster ovary cells by ATF4 overexpressionEngineering mammalian cells in bioprocessing - current achievements and future perspectives.Use of a protein engineering strategy to overcome limitations in the production of "Difficult to Express" recombinant proteins.Genetic analyses of Per.C6 cell clones producing a therapeutic monoclonal antibody regarding productivity and long-term stability.Disruption of the gene C12orf35 leads to increased productivities in recombinant CHO cell lines.High levels of histone H3 acetylation at the CMV promoter are predictive of stable expression in Chinese hamster ovary cells.Evaluating the interaction between UCOE and DHFR-linked amplification and stability of recombinant protein expression.It's time to regulate: coping with product-induced nongenetic clonal instability in CHO cell lines via regulated protein expression.Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins.Promoter methylation and transgene copy numbers predict unstable protein production in recombinant Chinese hamster ovary cell lines.A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies.Engineering of chaperone systems and of the unfolded protein response.Human T-lymphotropic virus tax activates human cytomegalovirus major-immediate early promoter and improves production of recombinant proteins in HEK293 cells.Correlation Between Expression of Recombinant Proteins and Abundance of H3K4Me3 on the Enhancer of Human Cytomegalovirus Major Immediate-Early Promoter.Effects of high passage cultivation on CHO cells: a global analysis.
P2860
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P2860
Molecular definition of predictive indicators of stable protein expression in recombinant NS0 myeloma cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Molecular definition of predic ...... recombinant NS0 myeloma cells.
@en
type
label
Molecular definition of predic ...... recombinant NS0 myeloma cells.
@en
prefLabel
Molecular definition of predic ...... recombinant NS0 myeloma cells.
@en
P2093
P356
P1476
Molecular definition of predic ...... recombinant NS0 myeloma cells.
@en
P2093
Alan J Dickson
Catherine M Bentley
Louise M Barnes
P2860
P304
P356
10.1002/BIT.10893
P577
2004-01-01T00:00:00Z