Differential ubiquitination defines the functional status of the tumor suppressor Smad4.
about
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transitionRegulation of TGF-β signal transduction by mono- and deubiquitylation of SmadsRegulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3Recombination-activating gene proteins: more regulation, pleaseUbiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targetingSmad4-expression is decreased in breast cancer tissues: a retrospective study.Mining the TRAF6/p62 interactome for a selective ubiquitination motif.Transforming growth factor beta promotes complexes between Smad proteins and the CCCTC-binding factor on the H19 imprinting control region chromatin.Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics.Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor β signaling.RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporterFunctional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-β signalling pathway.Hippo pathway phylogenetics predicts monoubiquitylation of Salvador and Merlin/Nf2Ubiquitin-dependent regulation of TGFbeta signaling in cancerSCF(beta-TrCP1) controls Smad4 protein stability in pancreatic cancer cellsAMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys.Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation.From pathways to networks: connecting dots by establishing protein-protein interaction networks in signaling pathways using affinity purification and mass spectrometry.Non-degradative ubiquitination in Smad-dependent TGF-β signalingRegulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers.Ubiquitin and proteasomes in transcriptionRegulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation.Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesisTo (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modificationsHypermethylation-mediated reduction of WWOX expression in intraductal papillary mucinous neoplasms of the pancreas.Regulating the stability of TGFbeta receptors and Smads.Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2Inhibition of pancreatic carcinoma cell growth in vitro by DPC4 gene transfection.Informatics approaches to understanding TGFbeta pathway regulation.Degradation of activated protein kinases by ubiquitination.Proteomic identification of protein ubiquitination events.SMAD4 mutations causing Myhre syndrome result in disorganization of extracellular matrix improved by losartanRegulation of TGF-beta signalling by protein phosphatases.Role of Smads in TGFβ signaling.Post-translational regulation of TGF-β receptor and Smad signaling.New insights into extracellular and post-translational regulation of TGF-β family signalling pathways.The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signalingReverse correlation of Jab1 and Smad4 in PANC-1 cells involved in the pathogenesis of pancreatic cancerBerbamine enhances the antineoplastic activity of gemcitabine in pancreatic cancer cells by activating transforming growth factor-β/Smad signaling.Transforming Growth Factor-β1 Modulates the Expression of Syndecan-4 in Cultured Vascular Endothelial Cells in a Biphasic Manner.
P2860
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P2860
Differential ubiquitination defines the functional status of the tumor suppressor Smad4.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Differential ubiquitination defines the functional status of the tumor suppressor Smad4.
@en
type
label
Differential ubiquitination defines the functional status of the tumor suppressor Smad4.
@en
prefLabel
Differential ubiquitination defines the functional status of the tumor suppressor Smad4.
@en
P2093
P2860
P356
P1476
Differential ubiquitination defines the functional status of the tumor suppressor Smad4.
@en
P2093
Anita Morén
Aristidis Moustakas
Carl-Henrik Heldin
Takeshi Imamura
Ulf Hellman
Yuri Inada
P2860
P304
33571-33582
P356
10.1074/JBC.M300159200
P407
P577
2003-06-05T00:00:00Z