The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts preferentially with the terminal repeats of the genome in vivo and this complex is sufficient for episomal DNA replication.
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Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5Kaposi's Sarcoma Herpesvirus Genome PersistenceMolecular Basis for Oligomeric-DNA Binding and Episome Maintenance by KSHV LANAKSHV infects a subset of human tonsillar B cells, driving proliferation and plasmablast differentiation.Intrabodies targeting the Kaposi sarcoma-associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells.Chromatin organization of gammaherpesvirus latent genomes.Kaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistenceUnbiased mutagenesis of MHV68 LANA reveals a DNA-binding domain required for LANA function in vitro and in vivo.Phosphorylation of the chromatin binding domain of KSHV LANAThe Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 N terminus is essential for chromosome association, DNA replication, and episome persistenceMechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and ReactivationRapid and quantitative assessment of KSHV LANA-mediated DNA replication.The internal Kaposi's sarcoma-associated herpesvirus LANA regions exert a critical role on episome persistenceKaposi's Sarcoma-Associated Herpesvirus Genome Replication, Partitioning, and Maintenance in Latency.Development of herpesvirus-based episomally maintained gene delivery vectors.The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc.The Kaposi Sarcoma Herpesvirus Latency-associated Nuclear Antigen DNA Binding Domain Dorsal Positive Electrostatic Patch Facilitates DNA Replication and Episome Persistence.Acetylated histone H3 and H4 mark the upregulated LMP2A promoter of Epstein-Barr virus in lymphoid cells.Murine gammaherpesvirus 68 LANA acts on terminal repeat DNA to mediate episome persistence.Investigation of the susceptibility of human cell lines to bovine herpesvirus 4 infection: demonstration that human cells can support a nonpermissive persistent infection which protects them against tumor necrosis factor alpha-induced apoptosis.Role of Kaposi's sarcoma-associated herpesvirus C-terminal LANA chromosome binding in episome persistence.Identification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.A short sequence immediately upstream of the internal repeat elements is critical for KSHV LANA mediated DNA replication and impacts episome persistenceKaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen: Replicating and Shielding Viral DNA during Viral Persistence.Cross-species conservation of episome maintenance provides a basis for in vivo investigation of Kaposi's sarcoma herpesvirus LANA.Disruption of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistence.The minimal replicator element of the Kaposi's sarcoma-associated herpesvirus terminal repeat supports replication in a semiconservative and cell-cycle-dependent manner.ORC, MCM, and histone hyperacetylation at the Kaposi's sarcoma-associated herpesvirus latent replication origin.KSHV and the Role of Notch Receptor Dysregulation in Disease Progression.Kaposi's sarcoma-associated herpesvirus LANA protein downregulates nuclear glycogen synthase kinase 3 activity and consequently blocks differentiation.Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigenKaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induces a strong bend on binding to terminal repeat DNA.Histone modification pattern of the T-cellular Herpesvirus saimiri genome in latency
P2860
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P2860
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts preferentially with the terminal repeats of the genome in vivo and this complex is sufficient for episomal DNA replication.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The latency-associated nuclear ...... for episomal DNA replication.
@en
type
label
The latency-associated nuclear ...... for episomal DNA replication.
@en
prefLabel
The latency-associated nuclear ...... for episomal DNA replication.
@en
P2093
P356
P1476
The latency-associated nuclear ...... for episomal DNA replication.
@en
P2093
Brian Lane
Elizabeth Horvath
György Fejér
Maria M Medveczky
P304
P356
10.1099/VIR.0.18940-0
P407
P577
2003-06-01T00:00:00Z