Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway.
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IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7Defining the mechanism by which IFN-beta dowregulates c-myc expression in human melanoma cells: pivotal role for human polynucleotide phosphorylase (hPNPaseold-35)Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene clusterPhosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 proteinCloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral stateInterferon-alpha-induced phosphorylation and activation of cytosolic phospholipase A2 is required for the formation of interferon-stimulated gene factor threeDivergent susceptibilities of human herpesvirus 6 variants to type I interferonsCollaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genesFunctional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signalingInteractions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complexThe amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptorA natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunityDifferent effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activationTRAIL Is a Novel Antiviral Protein against Dengue VirusBlockade of virus infection by human CD4+ T cells via a cytokine relay networkThe crystal structure of human interferon beta at 2.2-A resolutionMurine gammaherpesvirus 68 encoding open reading frame 11 targets TANK binding kinase 1 to negatively regulate the host type I interferon responseThe human type I interferon receptor. Identification of the interferon beta-specific receptor-associated phosphoproteinThe interferon alpha induced protein ISG12 is localized to the nuclear membraneStat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signalingDifferential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7Insertional mutagenesis in mice: new perspectives and toolsFormation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alphaCharacterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alphaHigh efficiency cell-specific targeting of cytokine activityMaking a grade: Sonic Hedgehog signalling and the control of neural cell fateSpecificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.A completely foreign receptor can mediate an interferon-gamma-like response.High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discoveryEarly dengue virus protein synthesis induces extensive rearrangement of the endoplasmic reticulum independent of the UPR and SREBP-2 pathwayJanus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferonsPlatelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteinsCatalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinaseInterferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinaseMutant human cells with constitutive activation of NF-kappaBA dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-alpha signaling.OAS1 polymorphisms are associated with susceptibility to West Nile encephalitis in horsesDeciphering the code for retroviral integration target site selection
P2860
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P2860
Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Use of a selectable marker reg ...... ions in the signaling pathway.
@en
type
label
Use of a selectable marker reg ...... ions in the signaling pathway.
@en
prefLabel
Use of a selectable marker reg ...... ions in the signaling pathway.
@en
P2093
P2860
P356
P1476
Use of a selectable marker reg ...... ions in the signaling pathway.
@en
P2093
P2860
P304
P356
10.1128/MCB.9.11.4605
P407
P577
1989-11-01T00:00:00Z