Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.
about
Cystic fibrosis transmembrane conductance regulator chloride channel blockers: Pharmacological, biophysical and physiological relevance.CFTR: Ligand exchange between a permeant anion ([Au(CN)2]-) and an engineered cysteine (T338C) blocks the pore.Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel.Architecture and functional properties of the CFTR channel pore.Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function.Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore.Regulation of CFTR chloride channel macroscopic conductance by extracellular bicarbonate.On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore.Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Molecular determinants and role of an anion binding site in the external mouth of the CFTR chloride channel pore.Evidence that extracellular anions interact with a site outside the CFTR chloride channel pore to modify channel properties.Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel.
P2860
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P2860
Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.
@en
type
label
Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.
@en
prefLabel
Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.
@en
P2860
P1476
Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.
@en
P2093
Xiandi Gong
P2860
P304
P356
10.1113/JPHYSIOL.2002.038216
P407
P577
2003-04-04T00:00:00Z