Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.
about
The human-bacterial pathogen protein interaction networks of Bacillus anthracis, Francisella tularensis, and Yersinia pestisGram-positive and gram-negative bacterial toxins in sepsis: a brief reviewInteractive effect of cigarette smoke extract and World Trade Center dust particles on airway cell cytotoxicityBinding of anthrax toxin to its receptor is similar to alpha integrin-ligand interactionsSelective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infectionReceptor-specific requirements for anthrax toxin delivery into cellsHuman alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequencesBinary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteinsCrystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptorGadd45 in the response of hematopoietic cells to genotoxic stressMembrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathwayAnthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune responseThe Ins and Outs of Anthrax ToxinBacterial Toxins as Pathogen Weapons Against PhagocytesAnthrax Toxins in Context of Bacillus anthracis Spores and Spore GerminationBacillus anthracis edema factor substrate specificity: evidence for new modes of actionCellular and physiological effects of anthrax exotoxin and its relevance to disease.Toxin-based therapeutic approachesThe structural basis for substrate and inhibitor selectivity of the anthrax lethal factorIdentification of small molecule inhibitors of anthrax lethal factorCrystal Structure of Bacillus anthracis Transpeptidase Enzyme CapDAlternative pre-approved and novel therapies for the treatment of anthraxAnthrax: A disease of biowarfare and public health importanceA docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substratesHistopathology in a murine model of anthraxSuppressive effects of anthrax lethal toxin on megakaryopoiesisRabbit and nonhuman primate models of toxin-targeting human anthrax vaccinesType IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophilaNLRP1-dependent pyroptosis leads to acute lung injury and morbidity in miceAnthrax toxin receptor 2-dependent lethal toxin killing in vivoA NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptideNod1/Nod2-mediated recognition plays a critical role in induction of adaptive immunity to anthrax after aerosol exposure.Transcriptional and apoptotic responses of THP-1 cells to challenge with toxigenic, and non-toxigenic Bacillus anthracis.Enhancement of anthrax lethal toxin cytotoxicity: a subset of monoclonal antibodies against protective antigen increases lethal toxin-mediated killing of murine macrophagesAnthrax lethal toxin paralyzes actin-based motility by blocking Hsp27 phosphorylation.TLR signaling is required for Salmonella typhimurium virulenceMicroglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.Reduced expression of CD45 protein-tyrosine phosphatase provides protection against anthrax pathogenesis.Host-pathogen interactions: a biological rendez-vous of the infectious nonself and danger models?Cationic polyamines inhibit anthrax lethal factor protease
P2860
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P2860
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.
@en
type
label
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.
@en
prefLabel
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.
@en
P356
P1433
P1476
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.
@en
P2093
Jin Mo Park
Zhi-Wei Li
P304
P356
10.1126/SCIENCE.1073163
P407
P577
2002-08-29T00:00:00Z