Structure of the transition state of gating in the acetylcholine receptor channel pore: a phi-value analysis.
about
End-plate acetylcholine receptor: structure, mechanism, pharmacology, and diseaseMammalian nicotinic acetylcholine receptors: from structure to functionChannel opening by anesthetics and GABA induces similar changes in the GABAA receptor M2 segmentPathways and Barriers for Ion Translocation through the 5-HT3A Receptor ChannelMutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystalsGating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallographyThe protein folding problemRecent advances in Cys-loop receptor structure and functionMechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure.Energy and structure of the M2 helix in acetylcholine receptor-channel gating.Dynamics of the acetylcholine receptor pore at the gating transition state.In silico models for the human alpha4beta2 nicotinic acetylcholine receptor.Gating of acetylcholine receptor channels: brownian motion across a broad transition state.Gating at the mouth of the acetylcholine receptor channel: energetic consequences of mutations in the alphaM2-capA speed limit for conformational change of an allosteric membrane protein.Energetics of gating at the apo-acetylcholine receptor transmitter binding site.A gating mechanism proposed from a simulation of a human alpha7 nicotinic acetylcholine receptorMaximum likelihood estimation of ion channel kinetics from macroscopic currentsMinimal structural rearrangement of the cytoplasmic pore during activation of the 5-HT3A receptor.Phi-value analysis and the nature of protein-folding transition statesPlasticity of acetylcholine receptor gating motions via rate-energy relationships.An energy-efficient gating mechanism in the acetylcholine receptor channel suggested by molecular and Brownian dynamics.Subunit symmetry at the extracellular domain-transmembrane domain interface in acetylcholine receptor channel gating.Probing ion-channel pores one proton at a time.Mapping heat exchange in an allosteric proteinFree-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channelsKey roles of hydrophobic rings of TM2 in gating of the alpha9alpha10 nicotinic cholinergic receptorCharge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.Life at the top: the transition state of AChR gating.Role of pairwise interactions between M1 and M2 domains of the nicotinic receptor in channel gatingFunctional anatomy of an allosteric protein.The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold.Conformational dynamics of the alphaM3 transmembrane helix during acetylcholine receptor channel gating.The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel.Nanosecond-timescale conformational dynamics of the human alpha7 nicotinic acetylcholine receptor.Effects of lipid-analog detergent solubilization on the functionality and lipidic cubic phase mobility of the Torpedo californica nicotinic acetylcholine receptorAcetylcholine receptor gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker.Agonist-activated ion channels.Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating.Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.
P2860
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P2860
Structure of the transition state of gating in the acetylcholine receptor channel pore: a phi-value analysis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Structure of the transition st ...... el pore: a phi-value analysis.
@en
type
label
Structure of the transition st ...... el pore: a phi-value analysis.
@en
prefLabel
Structure of the transition st ...... el pore: a phi-value analysis.
@en
P2093
P356
P1433
P1476
Structure of the transition st ...... nel pore: a phi-value analysis
@en
P2093
Anthony Auerbach
Claudio Grosman
Gisela D Cymes
P304
P356
10.1021/BI011864F
P407
P577
2002-04-01T00:00:00Z