Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.
about
Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screensSmurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cellsTGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcANon-redundant role of Shc in Erk activation by cytoskeletal reorganizationDecreased superoxide production in macrophages of long-lived p66Shc knock-out mice.Short interfering RNA-induced gene silencing is transmitted between cells from the mammalian central nervous systemThe Shc locus regulates insulin signaling and adiposity in mammalsSynthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.Memo mediates ErbB2-driven cell motility.Diversity in TAF proteomics: consequences for cellular differentiation and migration.The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism.TNFα signals via p66(Shc) to induce E-Selectin, promote leukocyte transmigration and enhance permeability in human endothelial cells.Met receptor-induced Grb2 or Shc signals both promote transformation of intestinal epithelial cells, albeit they are required for distinct oncogenic functions.Genomewide view of gene silencing by small interfering RNAsShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.How are genes measured? Examples from studies on iron metabolism in pregnancy.Functional genomics to new drug targets.p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria.Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosisThe p66Shc adapter protein regulates the morphogenesis and epithelial maturation of fetal mouse lungs.The adaptor proteins p66Shc and Grb2 regulate the activation of the GTPases ARF1 and ARF6 in invasive breast cancer cells.Tolerance for mutations and chemical modifications in a siRNA.Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant rat P2X3 receptor.p66shc inhibits pro-survival epidermal growth factor receptor/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells.ShRNA-mediated gene silencing of beta-catenin inhibits growth of human colon cancer cellsNon-canonical dynamic mechanisms of interaction between the p66Shc protein and Met receptorFiltering of ineffective siRNAs and improved siRNA design tool.Gene-level differential analysis at transcript-level resolution.Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation.Chronic Nicotine Exposure Reduces Antioxidant Function of Simvastatin in Renal Proximal Tubule Cells
P2860
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P2860
Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Isoform-specific knockdown and ...... A using small interfering RNA.
@en
type
label
Isoform-specific knockdown and ...... A using small interfering RNA.
@en
prefLabel
Isoform-specific knockdown and ...... A using small interfering RNA.
@en
P2093
P2860
P1433
P1476
Isoform-specific knockdown and ...... cA using small interfering RNA
@en
P2093
Malgorzata Kisielow
Michiaki Nagasawa
Sandra Kleiner
Yoshikuni Nagamine
P2860
P356
10.1042/0264-6021:3630001
P407
P50
P577
2002-04-01T00:00:00Z