Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a.
about
Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcriptionThe histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cellsSIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activitiesCo-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferasesThe replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1.Environmentally induced epigenetic transgenerational inheritance of phenotype and diseaseMammalian epigenetic mechanismsSurvival and Evolution of CRISPR-Cas System in Prokaryotes and Its ApplicationsChromatin remodeling, histone modifications, and DNA methylation-how does it all fit together?Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3LhNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencingNucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritanceAntidepressants inhibit DNA methyltransferase 1 through reducing G9a levelsDistribution, recognition and regulation of non-CpG methylation in the adult mammalian brain.Asymmetric strand segregation: epigenetic costs of genetic fidelity?Epigenetic regulation of estrogen receptor alpha gene expression in the mouse cortex during early postnatal development.Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase.A population-epigenetic model to infer site-specific methylation rates from double-stranded DNA methylation patterns.Cystathionine beta-synthase deficiency causes fat loss in mice.Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.Epigenetic contributors to the discordance of monozygotic twins.Epigenetic mechanisms and genome stability.Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)Environmental signaling and evolutionary change: can exposure of pregnant mammals to environmental estrogens lead to epigenetically induced evolutionary changes in embryos?Maintenance and regulation of DNA methylation patterns in mammals.CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiationSelective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA.A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding.Epigenetic aspects of fertilization and preimplantation development in mammals: lessons from the mouse.Feedback networks between microRNAs and epigenetic modifications in urological tumors.Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor.DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences.Genetic basis of MPN: Beyond JAK2-V617F.Linking immunity, epigenetics, and cancer in inflammatory bowel disease.Nucleosomes protect DNA from DNA methylation in vivo and in vitro.Phospho-ΔNp63α/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomasAchilles' heel of pluripotent stem cells: genetic, genomic and epigenetic variations during prolonged culture.Epigenetics: A primer for clinicians.
P2860
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P2860
Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Preferential methylation of un ...... DNA methyltransferase Dnmt3a.
@en
type
label
Preferential methylation of un ...... DNA methyltransferase Dnmt3a.
@en
prefLabel
Preferential methylation of un ...... DNA methyltransferase Dnmt3a.
@en
P2860
P356
P1476
Preferential methylation of un ...... o DNA methyltransferase Dnmt3a
@en
P2093
Tomoki Yokochi
P2860
P304
11735-11745
P356
10.1074/JBC.M106590200
P407
P577
2002-01-30T00:00:00Z