Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis.
about
Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathwayCalpastatin modulates APP processing in the brains of β-amyloid depositing but not wild-type miceSecretory granule membrane protein recycles through multivesicular bodiesNovel subtractive transcription-based amplification of mRNA (STAR) method and its application in search of rare and differentially expressed genes in AD brains.Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.Pyroglutamate-amyloid-β and glutaminyl cyclase are colocalized with amyloid-β in secretory vesicles and undergo activity-dependent, regulated secretion.Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice.Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's diseaseCharacterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations.Niemann-Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up.Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice.Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability.The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease.Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse.Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects.Autophagy in Alzheimer's disease.Lysosomal fusion dysfunction as a unifying hypothesis for Alzheimer's disease pathology.Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases.Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein.Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?Very-long-chain fatty acids activate lysosomal hydrolases in neonatal human skin tissue.Up-regulation of glycohydrolases in Alzheimer's Disease fibroblasts correlates with Ras activation.Control of amyloid-beta-peptide generation by subcellular trafficking of the beta-amyloid precursor protein and beta-secretase.Lysosome-associated membrane protein 1 (LAMP-1) in Alzheimer's disease.
P2860
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P2860
Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Alzheimer's disease-related ov ...... ution in beta-amyloidogenesis.
@en
type
label
Alzheimer's disease-related ov ...... ution in beta-amyloidogenesis.
@en
prefLabel
Alzheimer's disease-related ov ...... ution in beta-amyloidogenesis.
@en
P2093
P2860
P356
P1476
Alzheimer's disease-related ov ...... ution in beta-amyloidogenesis.
@en
P2093
Anne M Cataldo
Annette Hille-Rehfeld
Benjamin H Kao
Carolyn B Guerra
Jack Rohrer
Marc Mercken
Olivera M Grbovic
Pankaj Mehta
Paul M Mathews
Ralph A Nixon
P2860
P304
P356
10.1074/JBC.M108161200
P407
P577
2001-09-10T00:00:00Z