Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways
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Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathwayMechanisms of chronic JAK-STAT3-SOCS3 signaling in obesitySignal transducer and activator of transcription 5A/B in prostate and breast cancersSignal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesisErythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinaseErythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cellsErythroid cells rendered erythropoietin independent by infection with Friend spleen focus-forming virus show constitutive activation of phosphatidylinositol 3-kinase and Akt kinase: involvement of insulin receptor substrate-related adapter proteins.Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells.Growth factor-independent proliferation of erythroid cells infected with Friend spleen focus-forming virus is protein kinase C dependent but does not require Ras-GTP.The significance of tetramerization in promoter recruitment by Stat5.The effect of erythropoietin on normal and neoplastic cells.Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5.Erythroblast transformation by the friend spleen focus-forming virus is associated with a block in erythropoietin-induced STAT1 phosphorylation and DNA binding and correlates with high expression of the hematopoietic phosphatase SHP-1.A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5Epo receptors are not detectable in primary human tumor tissue samplesIdentification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activationErythropoietin-induced erythroid differentiation of the human erythroleukemia cell line TF-1 correlates with impaired STAT5 activationAn IL-2 response element in the human IL-2 receptor alpha chain promoter is a composite element that binds Stat5, Elf-1, HMG-I(Y) and a GATA family protein.Mammalian granulocyte-macrophage colony-stimulating factor receptor expressed in primary avian hematopoietic progenitors: lineage-specific regulation of proliferation and differentiationErythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.Naturally occurring dominant negative variants of Stat5.Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha geneBiology and significance of the JAK/STAT signalling pathways.Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.The erythropoietin receptor: molecular structure and hematopoietic signaling pathways.Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells.TRPC3 activation by erythropoietin is modulated by TRPC6.Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.Phosphorylation of erythropoietin receptors in the endoplasmic reticulum by pervanadate-mediated inhibition of tyrosine phosphatases.
P2860
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P2860
Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways
@en
type
label
Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways
@en
prefLabel
Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways
@en
P2093
P2860
P1433
P1476
Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways
@en
P2093
P2860
P304
P407
P577
1995-06-01T00:00:00Z