The smaller human VH gene families display remarkably little polymorphism.
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Somatic hypermutation introduces insertions and deletions into immunoglobulin V genesClonally-related immunoglobulin VH domains and nonrandom use of DH gene segments in rheumatoid arthritis synovium9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activityHuman rheumatoid factors with restrictive specificity for rabbit immunoglobulin G: auto- and multi-reactivity, diverse VH gene segment usage and preferential usage of V lambda IIIb.Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes.Chromosomal organization of the heavy chain variable region gene segments comprising the human fetal antibody repertoire.Isolation of germinal centerlike events from human spleen RNA. Somatic hypermutation of a clonally related VH6DJH rearrangement expressed with IgM, IgG, and IgA.Naturally occurring anti-i/I cold agglutinins may be encoded by different VH3 genes as well as the VH4.21 gene segmentThe physical organization of the human immunoglobulin heavy chain gene complex.Defining the genetic origins of three rheumatoid synovium-derived IgG rheumatoid factors.Limited B cell repertoire in severe combined immunodeficient mice engrafted with peripheral blood mononuclear cells derived from immunodeficient or normal humans.Analysis of somatic mutation in five B cell subsets of human tonsil.Nonuniform linkage disequilibrium within a 1,500-kb region of the human immunoglobulin heavy-chain complexSomatic mutation of human immunoglobulin V genes in the X-linked HyperIgM syndrome.Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles.Sequence analyses of three immunoglobulin G anti-virus antibodies reveal their utilization of autoantibody-related immunoglobulin Vh genes, but not V lambda genes.Superantigen properties of a human sialoprotein involved in gut-associated immunity.Ethnic differences of polymorphism of an immunoglobulin VH3 gene.Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of developmentMemory B lymphocytes migrate to bone marrow in humansRegulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance.Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven responseExtensive and selective mutation of a rearranged VH5 gene in human B cell chronic lymphocytic leukemia.Molecular characterization of IgA- and/or IgG-switched chronic lymphocytic leukemia B cellsComplete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and IgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient.Structure of the VH and VL segments of polyreactive and monoreactive human natural antibodies to HIV-1 and Escherichia coli beta-galactosidaseStructure and expression of human germline VH transcriptsMolecular evolution of the human immunoglobulin E response: high incidence of shared mutations and clonal relatedness among epsilon VH5 transcripts from three unrelated patients with atopic dermatitisLack of extensive mutations in the VH5 genes used in common B cell chronic lymphocytic leukemia.Diversification, not use, of the immunoglobulin VH gene repertoire is restricted in DiGeorge syndrome.Molecular characterization of a cross-reactive idiotope on human immunoglobulins utilizing the VH4-21 gene segment.Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice.Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells.Clonal evolution of a follicular lymphoma: evidence for antigen selection.Molecular characterization of five human anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response.Immunoglobulin variable heavy chain cDNA sequence from a patient with X-linked agammaglobulinemia.The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement.Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sectionsGermline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.
P2860
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P2860
The smaller human VH gene families display remarkably little polymorphism.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The smaller human VH gene families display remarkably little polymorphism.
@en
type
label
The smaller human VH gene families display remarkably little polymorphism.
@en
prefLabel
The smaller human VH gene families display remarkably little polymorphism.
@en
P2093
P2860
P1433
P1476
The smaller human VH gene families display remarkably little polymorphism.
@en
P2093
P2860
P304
P407
P577
1989-12-01T00:00:00Z