Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.
about
Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cellsRepression of the HIV-1 5' LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factorsTargeting serous epithelial ovarian cancer with designer zinc finger transcription factorsTherapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesA rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoterTargeted genome editing in human cells with zinc finger nucleases constructed via modular assemblyZinc Finger Tools: custom DNA-binding domains for transcription factors and nucleasesHighly specific zinc finger proteins obtained by directed domain shuffling and cell-based selectionSuppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels.Applications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology ResearchEnabling functional genomics with genome engineeringEpigenetic Editing: On the Verge of Reprogramming Gene Expression at WillSite-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteinsDevelopment of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factorsEngineering polydactyl zinc-finger transcription factorsSynthetic reversal of epigenetic silencingHighly efficient endogenous human gene correction using designed zinc-finger nucleasesVEGF gene therapy: therapeutic angiogenesis in the clinic and beyondDevelopment of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factorsTargeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked BehaviorCRISPR RNA-guided activation of endogenous human genesStabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells.Upregulation of endogenous HMOX1 expression by a computer-designed artificial transcription factor.Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.Scanning the human genome with combinatorial transcription factor libraries.Human zinc fingers as building blocks in the construction of artificial transcription factors.Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors.Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool.Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based methodOligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arraysPositive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production.Modular system for the construction of zinc-finger libraries and proteins.Zinc finger nucleases as tools to understand and treat human diseases.Delayed administration of a bio-engineered zinc-finger VEGF-A gene therapy is neuroprotective and attenuates allodynia following traumatic spinal cord injury.Probing the DNA-binding affinity and specificity of designed zinc finger proteinsCustom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes.Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors.Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors.
P2860
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P2860
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Regulation of an endogenous lo ...... r endothelial growth factor A.
@en
type
label
Regulation of an endogenous lo ...... r endothelial growth factor A.
@en
prefLabel
Regulation of an endogenous lo ...... r endothelial growth factor A.
@en
P2093
P2860
P356
P1476
Regulation of an endogenous lo ...... r endothelial growth factor A.
@en
P2093
Eisenberg SP
Jamieson AC
P2860
P304
11323-11334
P356
10.1074/JBC.M011172200
P407
P577
2001-01-05T00:00:00Z