Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling.
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ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent mannerErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cellsActivation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoproteinCucurbitacins - a promising target for cancer therapyMesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitinationSTAT3 as a therapeutic target in head and neck cancerNecdin, a negative growth regulator, is a novel STAT3 target gene down-regulated in human cancerEGFR-targeted therapy in malignant glioma: novel aspects and mechanisms of drug resistance.Honokiol inhibits epithelial-mesenchymal transition in breast cancer cells by targeting signal transducer and activator of transcription 3/Zeb1/E-cadherin axis.DAB2IP loss confers the resistance of prostate cancer to androgen deprivation therapy through activating STAT3 and inhibiting apoptosisHepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replicationEpidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells.A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cellsStat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis.Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumoursSTAT proteins: novel molecular targets for cancer drug discovery.Interleukin-6 is an important mediator for mitochondrial DNA repair after alcoholic liver injury in miceEfficient gene expression profiling of laser-microdissected melanoma metastases.Downregulation of signal transducer and activator of transcription 3 by sorafenib: a novel mechanism for hepatocellular carcinoma therapy.Activated Src abrogates the Myc requirement for the G0/G1 transition but not for the G1/S transition.Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer.The role of hepatocyte growth factor (scatter factor) in epithelial-mesenchymal transition and breast cancer.WT1 promotes cell proliferation in non-small cell lung cancer cell lines through up-regulating cyclin D1 and p-pRb in vitro and in vivo.Pharmacogenomic strategies for developing customized chemotherapy in non-small cell lung cancer.Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.Herbal remedy magnolol suppresses IL-6-induced STAT3 activation and gene expression in endothelial cells.Essential role of Stat3 in PI3K-induced oncogenic transformationEupatilin Inhibits Gastric Cancer Cell Growth by Blocking STAT3-Mediated VEGF Expression.SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines.CUEDC2 (CUE domain-containing 2) and SOCS3 (suppressors of cytokine signaling 3) cooperate to negatively regulate Janus kinase 1/signal transducers and activators of transcription 3 signaling.RACK1 regulates G1/S progression by suppressing Src kinase activity.Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer.Peptide modulators of Src activity in G1 regulate entry into S phase and proliferation of NIH 3T3 cells.Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesisSTAT proteins as novel targets for cancer drug discovery.Signal transducers and activators of transcription: insights into the molecular basis of oral cancer.Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes.Silencing STAT3 with short hairpin RNA enhances radiosensitivity of human laryngeal squamous cell carcinoma xenografts in vivo.In vivo induction of apoptosis by fucoxanthin, a marine carotenoid, associated with down-regulating STAT3/EGFR signaling in sarcoma 180 (S180) xenografts-bearing mice.
P2860
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P2860
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Induction of p21WAF1/CIP1 and ...... of activated STAT3 signaling.
@en
type
label
Induction of p21WAF1/CIP1 and ...... of activated STAT3 signaling.
@en
prefLabel
Induction of p21WAF1/CIP1 and ...... of activated STAT3 signaling.
@en
P2093
P2860
P356
P1433
P1476
Induction of p21WAF1/CIP1 and ...... of activated STAT3 signaling.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203947
P407
P577
2000-11-01T00:00:00Z
P5875
P6179
1029504869