On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.
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Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progressionSpecialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factorPrediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast cell linesNuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinasesThe structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent rolesThe APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exitMitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibitedInhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit.DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression.Cell cycle-related cyclin b1 quantificationThe ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancerNS1- and minute virus of mice-induced cell cycle arrest: involvement of p53 and p21(cip1)Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.Cellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment.Novel functions of the phosphatase SHP2 in the DNA replication and damage checkpoints.Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model.A data-driven, mathematical model of mammalian cell cycle regulation.A systems biology dynamical model of mammalian G1 cell cycle progression.The role of modelling in identifying drug targets for diseases of the cell cycleRole for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosisA subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase.Critical reanalysis of the methods that discriminate the activity of CDK2 from CDK1Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cellsRobust mitotic entry is ensured by a latching switchUnderstanding the limitations of radiation-induced cell cycle checkpoints.Differential prognostic impact of the cyclins E and B in premenopausal and postmenopausal women with lymph node-negative breast cancer.A fluorescent probe for detection of an intracellular prognostic indicator in early-stage cancer.Phosphorylation of the N-terminal domain of p48 Ebp1 by CDK2 is required for tumorigenic function of p48.Detection of a prognostic indicator in early-stage cancer using functionalized graphene-based peptide sensors.Easy Identification of Residues Involved on Structural Differences Between Nonphosphorylated and Phosphorylated CDK2Cyclin A Complexes Using Two-Dimensional Networks.Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures.Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycleThe kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint.Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosisNovel properties of the cyclin encoded by Human Herpesvirus 8 that facilitate exit from quiescence.Depletion of p31comet protein promotes sensitivity to antimitotic drugs.Differential mode of regulation of the checkpoint kinases CHK1 and CHK2 by their regulatory domains.Orderly inactivation of the key checkpoint protein mitotic arrest deficient 2 (MAD2) during mitotic progression.Reduced graphene oxide upconversion nanoparticle hybrid for electrochemiluminescent sensing of a prognostic indicator in early-stage cancer.
P2860
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P2860
On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
On the concentrations of cycli ...... racts of cultured human cells.
@en
type
label
On the concentrations of cycli ...... racts of cultured human cells.
@en
prefLabel
On the concentrations of cycli ...... racts of cultured human cells.
@en
P2093
P356
P1433
P1476
On the concentrations of cycli ...... tracts of cultured human cells
@en
P2093
P304
P356
10.1021/BI0009643
P407
P50
P577
2000-08-01T00:00:00Z