Abl tyrosine kinase in signal transduction and cell-cycle regulation.
about
Bruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding proteinFunctional interaction between c-Abl and the p21-activated protein kinase gamma-PAKArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disksRegulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinaseCharacterization of a novel member of the DOK family that binds and modulates Abl signalingc-Abl kinase regulates the protein binding activity of c-CrkMutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinasec-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activationc-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding proteinNovel targeted therapies for Bcr-Abl positive acute leukemias: beyond STI571.Association of tyrosine phosphatase SHP-2 with F-actin at low cell densitiesMultiple signaling interactions of Abl and Arg kinases with the EphB2 receptorTransforming pathways activated by the v-Abl tyrosine kinaseIntegrins regulate the association and phosphorylation of paxillin by c-AblParallel Chemical Protein Synthesis on a Surface Enables the Rapid Analysis of the Phosphoregulation of SH3 Domains.Differences in structural elements of Bcr-Abl oncoprotein isoforms in Chronic Myelogenous Leukemia.Inhibition of c-Abl tyrosine kinase activity by filamentous actin.Interaction of the N-methyl-D-aspartic acid receptor NR2D subunit with the c-Abl tyrosine kinase.Regulation of human c-Abl tyrosine kinase activity in Xenopus oocytes and acceleration of progesterone-induced G2/M transition by oncogenic forms.Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein-protein interactions of EnabledDifferential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins.c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGFSrc homology 2 domain as a specificity determinant in the c-Abl-mediated tyrosine phosphorylation of the RNA polymerase II carboxyl-terminal repeated domainSpecific association of Type I c-Abl with Ran GTPase in lipopolysaccharide-mediated differentiation.Effect of thyroid hormone responsive protein (THRP) expression on PC12 cell survival.RNA interference screen identifies Abl kinase and PDGFR signaling in Chlamydia trachomatis entry.Assay development and high-throughput screening of small molecular c-Abl kinase activators.p53 mediates apoptotic crisis in primary Abelson virus-transformed pre-B cells.p53 deficiency increases transformation by v-Abl and rescues the ability of a C-terminally truncated v-Abl mutant to induce pre-B lymphoma in vivo.Tyrosine kinase inhibitors: from rational design to clinical trials.Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90.Structure-guided optimization of small molecule c-Abl activatorsIntegrins, oncogenes, and anchorage independence.Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disordersRegulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein.Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms.p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation.Increased sensitivity to apoptotic stimuli in c-abl-deficient progenitor B-cell linesEffect of c-Abl tyrosine kinase on the cellular response to paclitaxel-induced microtubule damage.Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.
P2860
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P2860
Abl tyrosine kinase in signal transduction and cell-cycle regulation.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Abl tyrosine kinase in signal transduction and cell-cycle regulation.
@en
type
label
Abl tyrosine kinase in signal transduction and cell-cycle regulation.
@en
prefLabel
Abl tyrosine kinase in signal transduction and cell-cycle regulation.
@en
P1476
Abl tyrosine kinase in signal transduction and cell-cycle regulation.
@en
P2093
P356
10.1016/S0959-437X(05)80338-7
P577
1993-02-01T00:00:00Z