DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.
about
Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytesBeyond DNA repair: DNA-PK function in cancerATM phosphorylates histone H2AX in response to DNA double-strand breaksRegulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouseATM: a mediator of multiple responses to genotoxic stress.Genetic evidence of a role for ATM in functional interaction between human T-cell leukemia virus type 1 Tax and p53.The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinaseDNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice.p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK.Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest.EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastomaDistinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cellsCleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.Low energy proton beam induces efficient cell killing in A549 lung adenocarcinoma cells.Time and dose-dependent activation of p53 serine 15 phosphorylation among cell lines with different radiation sensitivity.Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV.DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis.Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation.Regulation of ubiquitination and degradation of p53 in unstressed cells through C-terminal phosphorylation.Role of DNA-dependent protein kinase in neuronal survival.Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase.
P2860
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P2860
DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.
@en
type
label
DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.
@en
prefLabel
DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.
@en
P2093
P2860
P356
P1476
DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.
@en
P2093
Crissman HA
Kurimasa A
P2860
P304
17139-17143
P356
10.1074/JBC.274.24.17139
P407
P577
1999-06-01T00:00:00Z