DNA-dependent protein kinase-independent activation of p53 in response to DNA damage. - Wikidata - awgldk - TriplyDB

DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.

DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.

http://www.wikidata.org/entity/Q40950612

about

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes Beyond DNA repair: DNA-PK function in cancer ATM phosphorylates histone H2AX in response to DNA double-strand breaks Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2 DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse ATM: a mediator of multiple responses to genotoxic stress.Genetic evidence of a role for ATM in functional interaction between human T-cell leukemia virus type 1 Tax and p53.The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice.p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK.Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest.EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.Low energy proton beam induces efficient cell killing in A549 lung adenocarcinoma cells.Time and dose-dependent activation of p53 serine 15 phosphorylation among cell lines with different radiation sensitivity.Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV.DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis.Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation.Regulation of ubiquitination and degradation of p53 in unstressed cells through C-terminal phosphorylation.Role of DNA-dependent protein kinase in neuronal survival.Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase.

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P2860

DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.

http://www.wikidata.org/entity/Q40950612

description

1999 nî lūn-bûn

@nan

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

1999年论文

@zh

1999年论文

@zh-cn

name

DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.

@en

type

label

DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.

@en

prefLabel

DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.

@en

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P356

JBC.274.24.17139

P1433

Journal of Biological Chemistry

P1476

DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.

@en

P2093

Abe M

http://www.w3.org/2001/XMLSchema#string

Araki R

http://www.w3.org/2001/XMLSchema#string

Burma S

http://www.w3.org/2001/XMLSchema#string

Chen DJ

http://www.w3.org/2001/XMLSchema#string

Crissman HA

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Kurimasa A

http://www.w3.org/2001/XMLSchema#string

Li GC

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Ouyang H

http://www.w3.org/2001/XMLSchema#string

Taya Y

http://www.w3.org/2001/XMLSchema#string

Xie G

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

Enhanced phosphorylation of p53 by ATM in response to DNA damage

Allosteric activation of latent p53 tetramers

p53: puzzle and paradigm

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells.

Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis.

DNA damage induces phosphorylation of the amino terminus of p53

Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice

P304

17139-17143

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scholarly article

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10.1074/JBC.274.24.17139

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P433

24

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P478

274

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1999-06-01T00:00:00Z

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P5875

12941005

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10358069

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