Smad4/DPC4 and Smad3 mediate transforming growth factor-beta (TGF-beta) signaling through direct binding to a novel TGF-beta-responsive element in the human plasminogen activator inhibitor-1 promoter.
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Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoterThrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cellsRequirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signalingGetting 'Smad' about obesity and diabetesFunctional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3RETRACTED: TGFβ1 signaling via αVβ6 integrinGroup 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability.The prothrombotic tendency in metabolic syndrome: focus on the potential mechanisms involved in impaired haemostasis and fibrinolytic balanceParticipation of Smad2, Smad3, and Smad4 in transforming growth factor beta (TGF-beta)-induced activation of Smad7. THE TGF-beta response element of the promoter requires functional Smad binding element and E-box sequences for transcriptional regulaIdentification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-beta actionIdentification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor betaFLRG, an activin-binding protein, is a new target of TGFbeta transcription activation through Smad proteinsGlucocorticoids activate TGF-beta induced PAI-1 and CTGF expression in rat hepatocytesAn integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules.Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance.TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway.Requirement of a dynein light chain in TGFbeta/Smad3 signaling.Smad6s regulates plasminogen activator inhibitor-1 through a protein kinase C-beta-dependent up-regulation of transforming growth factor-beta.Vascular biology of metabolic syndromeTransforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss.Linoleic acid enhances angiogenesis through suppression of angiostatin induced by plasminogen activator inhibitor 1.Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathwayStatins Increase Plasminogen Activator Inhibitor Type 1 Gene Transcription through a Pregnane X Receptor Regulated Element.USP11 augments TGFβ signalling by deubiquitylating ALK5.Aortic Remodelling Is Improved by 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside Involving the Smad3 Pathway in Spontaneously Hypertensive Rats.Transforming growth factor beta enhances the glucocorticoid response of the mouse mammary tumor virus promoter through Smad and GA-binding proteinsAdipocytokines and the metabolic complications of obesity.Thrombospondin 1 as a novel biological marker of obesity and metabolic syndromeInsulin acts through FOXO3a to activate transcription of plasminogen activator inhibitor type 1.Biology of metabolic syndrome in a vascular patient.A Forkhead/winged helix-related transcription factor mediates insulin-increased plasminogen activator inhibitor-1 gene transcription.An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*.Glycated albumin activates PAI-1 transcription through Smad DNA binding sites in mesangial cells.Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway.Increased cell migration and plasticity in Nrf2-deficient cancer cell lines.Nuclear factor YY1 inhibits transforming growth factor beta- and bone morphogenetic protein-induced cell differentiationSmad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta.The amyloid-beta peptide suppresses transforming growth factor-beta1-induced matrix metalloproteinase-2 production via Smad7 expression in human monocytic THP-1 cells.
P2860
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P2860
Smad4/DPC4 and Smad3 mediate transforming growth factor-beta (TGF-beta) signaling through direct binding to a novel TGF-beta-responsive element in the human plasminogen activator inhibitor-1 promoter.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Smad4/DPC4 and Smad3 mediate t ...... ctivator inhibitor-1 promoter.
@en
type
label
Smad4/DPC4 and Smad3 mediate t ...... ctivator inhibitor-1 promoter.
@en
prefLabel
Smad4/DPC4 and Smad3 mediate t ...... ctivator inhibitor-1 promoter.
@en
P2093
P2860
P356
P1476
Smad4/DPC4 and Smad3 mediate t ...... ctivator inhibitor-1 promoter.
@en
P2093
P2860
P304
29287-29290
P356
10.1074/JBC.273.45.29287
P407
P577
1998-11-01T00:00:00Z