Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit.
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Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gatingModulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domainTbx20 regulates a genetic program essential to adult mouse cardiomyocyte functionCardiovascular Action of Insulin in Health and Disease: Endothelial L-Arginine Transport and Cardiac Voltage-Dependent Potassium ChannelsIon Channels in the HeartCaMKII regulation of cardiac K channelsTargeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f)Functional consequences of the arrhythmogenic G306R KvLQT1 K+ channel mutant probed by viral gene transfer in cardiomyocytesEvidence for the presence of a novel Kv4-mediated A-type K(+) channel-modifying factorInput-specific immunolocalization of differentially phosphorylated Kv4.2 in the mouse brainC-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2Kv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neuronesThe homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradientInducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotypeMutant analysis of the Shal (Kv4) voltage-gated fast transient K+ channel in Caenorhabditis elegansInherited long QT syndromes: a paradigm for understanding arrhythmogenesis.Mouse models of long QT syndrome.MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult heartsMolecular determinants of cardiac transient outward potassium current (I(to)) expression and regulationShal/K(v)4 channels are required for maintaining excitability during repetitive firing and normal locomotion in Drosophila.Molecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium.Molecular dissection of cardiac repolarization by in vivo Kv4.3 gene transferThe consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.Proteomic analysis highlights the molecular complexities of native Kv4 channel macromolecular complexes.Remodeling of early-phase repolarization: a mechanism of abnormal impulse conduction in heart failureMicroRNA-301a mediated regulation of Kv4.2 in diabetes: identification of key modulators.Dynamic remodeling of K+ and Ca2+ currents in cells that survived in the epicardial border zone of canine healed infarcted heartBlockade by N-3 polyunsaturated fatty acid of the Kv4.3 current stably expressed in Chinese hamster ovary cells.A-type potassium currents in smooth muscle.High level of oxygen treatment causes cardiotoxicity with arrhythmias and redox modulationIntercalated disc-associated protein, mXin-alpha, influences surface expression of ITO currents in ventricular myocytes.Intracellular Ca2+ release underlies the development of phase 2 in mouse ventricular action potentials.Distinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1.Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure.Mathematical modeling mechanisms of arrhythmias in transgenic mouse heart overexpressing TNF-αTransient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms.KChIP2 genotype dependence of transient outward current (Ito) properties in cardiomyocytes isolated from male and female mice.Four kinetically distinct depolarization-activated K+ currents in adult mouse ventricular myocytes.Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles.
P2860
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P2860
Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Functional knockout of the tra ...... nt-negative Kv4 alpha subunit.
@en
type
label
Functional knockout of the tra ...... nt-negative Kv4 alpha subunit.
@en
prefLabel
Functional knockout of the tra ...... nt-negative Kv4 alpha subunit.
@en
P2093
P356
P1433
P1476
Functional knockout of the tra ...... nt-negative Kv4 alpha subunit.
@en
P2093
P304
P356
10.1161/01.RES.83.5.560
P577
1998-09-01T00:00:00Z